HLA-DP/DR/DQ Antibody (PdV5.2): sc-130013

HLA-DP/DR/DQ Antibody (PdV5.2) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect HLA-DP, HLA-DR, and HLA-DQ proteins, collectively known as MHC class II molecules. These proteins are predominantly located on the surface of antigen-presenting cells, including B lymphocytes, dendritic cells, and macrophages, as well as within intracellular endosomal and lysosomal compartments. The precise cellular localization of HLA-DP/DR/DQ is essential for their critical role in presenting exogenous antigens to CD4+ helper T cells, thereby initiating and regulating adaptive immune responses. HLA-DP/DR/DQ (PdV5.2) monoclonal antibody enables detailed study of antigen presentation mechanisms, immune system functionality, and the identification of pathological conditions such as autoimmune diseases and cancers. Anti-HLA-DP/DR/DQ antibody (PdV5.2) is validated for use in a variety of applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry (IHC), and functional assays, providing versatility for diverse research and diagnostic protocols. Additionally, HLA-DP/DR/DQ monoclonal antibody (PdV5.2) is available in both non-conjugated and multiple conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, ensuring compatibility with a wide range of experimental techniques. HLA-DP/DR/DQ (PdV5.2) monoclonal antibody is recommended for scientists investigating the complexities of the immune system and its implications in health and disease, facilitating advancements in immunological research, diagnostics, and the development of targeted therapies.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HLA-DP/DR/DQ Antibody (PdV5.2) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-HLA-DP/DR/DQ Antibody (PdV5.2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HLA-DP/DR/DQ Antibody (PdV5.2) Specifications

Alternate Product Name: human leukocyte antigen (HLA) HLA-DP/ HLA-DR/ HLA-DQ

Product Clone Name: PdV5.2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: HLA-DP

Epitope Species: human

Product Reactivity/Detection: HLA-DP, HLA-DR and HLA-DQ

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), functional assay

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for HLA-DP/DR/DQ Antibody (PdV5.2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, L: Azide-Free, PE: Phycoerythrin

The preferred HLA-DR antibody is HLA-DR Antibody (L243): sc-18875.