HLA-DP Antibody (OX76): sc-53077
- HLA-DP Antibody (OX76) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against RT1Bac of rat origin
- recommended for detection of HLA-DP of mouse and rat origin by FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HLA-DP Antibody (OX76). These reagents are now offered in bundles with HLA-DP Antibody (OX76) (see ordering information below).
HLA-DP Antibody (OX76) is a mouse monoclonal IgG2a kappa light chain antibody, engineered to target the HLA-DP molecule, also known as Human Leukocyte Antigen DP or HLA-DPB. Anti-HLA-DP antibody (OX76) recognizes an epitope derived from RT1Bac of rat origin, enabling effective detection of HLA-DP in both mouse and rat species through flow cytometry (FCM). HLA-DP is a pivotal member of the Major Histocompatibility Complex (MHC) class II family, responsible for presenting antigenic peptides to CD4+ helper T cells, which is essential for initiating and regulating adaptive immune responses. Post-translational modifications, particularly glycosylation, are critical for HLA-DP as they ensure proper protein folding, stability, and surface expression, thereby facilitating efficient antigen presentation and immune recognition. HLA-DP monoclonal antibody (OX76) serves as an indispensable tool for researchers investigating immune system functions, autoimmune disorders, and transplant biology, where HLA-DP expression and regulation play a significant role. By targeting a key molecule involved in immune modulation, anti-HLA-DP antibody (OX76) supports the advancement of immunological research and the development of therapeutic strategies aimed at manipulating MHC class II pathways.
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HLA-DP Antibody (OX76) References:
- Effect of HLA-DR matching on rejection after cardiac transplantation. | Cochrane, A., et al. 1992. Transplant Proc. 24: 169-70. PMID: 1539227
- [Macrophages and HLA-DR expression in proliferative vitreoretinopathy]. | Scheiffarth, OF., et al. 1990. Fortschr Ophthalmol. 87: 340-3. PMID: 2210559
- Decreased Human Leukocyte Antigen DR on Circulating Monocytes Expression After Severe Pediatric Trauma: An Exploratory Report. | Cour-Andlauer, F., et al. 2021. Pediatr Crit Care Med. 22: e314-e323. PMID: 33137010
- HLA-DR antigen on human trophoblast. | Brami, CJ., et al. 1983. Am J Reprod Immunol (1980). 3: 165-74. PMID: 6349390
- Cyclosporin A blocks receptors for HLA-DR antigens on T cells. | Palacios, R. and Möller, G. 1981. Nature. 290: 792-4. PMID: 6783967
- HLA-DR typing in cadaver kidney donors and recipients in Copenhagen. | Thomsen, M., et al. 1981. Scand J Urol Nephrol Suppl. 64: 79-86. PMID: 6815796
- HLA-DR matching in cadaveric renal transplantation. | . 1981. N Engl J Med. 304: 488-9. PMID: 7005684
- Repeat HLA-DR mismatches in second transplants. | Ting, A. and Morris, PJ. 1978. Lancet. 2: 148-9. PMID: 78340
- Ichthyosis-associated spheroid corneal degeneration in HLA-DR identical brothers. | Sharma, K., et al. 1993. Indian J Ophthalmol. 41: 191-3. PMID: 8005655
- Prospective HLA-DR matching in penetrating keratoplasty. | Van Der Hauwaert, N., et al. 1995. Bull Soc Belge Ophtalmol. 257: 27-30. PMID: 8696521
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HLA-DP Antibody (OX76) | sc-53077 | 200 µg/ml | $322.00 | |||
HLA-DP Antibody (OX76): m-IgG Fc BP-HRP Bundle | sc-536885 | 200 µg Ab; 10 µg BP | $361.00 | |||
HLA-DP Antibody (OX76): m-IgGκ BP-HRP Bundle | sc-534056 | 200 µg Ab; 40 µg BP | $361.00 | |||
HLA-DP Antibody (OX76): m-IgG2a BP-HRP Bundle | sc-547891 | 200 µg Ab; 10 µg BP | $361.00 | |||
HLA-DP Antibody (OX76) FITC | sc-53077 FITC | 200 µg/ml | $336.00 | |||
HLA-DP Antibody (OX76) PE | sc-53077 PE | 200 µg/ml | $349.00 |