Date published: 2025-10-15

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HIV-2 gp36 Antibody (3B10/G2): sc-52421

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Datasheets
  • HIV-2 gp36 Antibody (3B10/G2) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against HIV2 recombinant antigen 00114-V
  • recommended for detection of HIV-2 by WB and IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-2 gp36 Antibody (3B10/G2). This work is in progress.

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    HIV-2 gp36 Antibody (3B10/G2) is a mouse monoclonal IgG1 antibody that specifically detects HIV-2 gp36 in HIV-2 by western blotting (WB) and immunoprecipitation (IP). HIV-2 gp36 is a crucial transmembrane protein located in the viral envelope of HIV-2, playing a significant role in host cell infection. HIV-2 gp36 binds to putative cellular receptor proteins P45 and P62, facilitating viral entry into target cells. Understanding HIV-2 gp36 function remains vital, as anti-HIV-2 gp36 antibody (3B10/G2) serves as a valuable research tool for studying HIV-2 pathogenesis and developing effective treatments.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    HIV-2 gp36 Antibody (3B10/G2) References:

    1. HIV-2 transmembrane protein gp36 binds to the putative cellular receptor proteins P45 and P62.  |  Chen, YH., et al. 2000. Immunobiology. 201: 317-22. PMID: 10776788
    2. Recombinant fusion proteins for haemagglutination-based rapid detection of antibodies to HIV in whole blood.  |  Gupta, A., et al. 2001. J Immunol Methods. 256: 121-40. PMID: 11516760
    3. Specific synthetic peptides for detection of and discrimination between HIV-1 and HIV-2 infection.  |  Broliden, PA., et al. 1991. J Acquir Immune Defic Syndr (1988). 4: 952-8. PMID: 1679844
    4. Performance characteristics of a novel immunoassay based on hybrid Ty virus-like particles (Ty-VLPs): rapid differentiation between HIV-1 and HIV-2 infection.  |  Gilmour, JE., et al. 1990. AIDS. 4: 967-73. PMID: 2124493
    5. Early and specific diagnosis of seropositivity to HIVs by an enzyme-linked immunosorbent assay using env-derived synthetic peptides.  |  Fenouillet, E., et al. 1990. AIDS. 4: 1137-40. PMID: 2282186
    6. [Evaluation of the immobilization of one HIV-2 gp36 peptide in nitrocellulose membrane].  |  Díaz Herrera, DF., et al. 2011. Rev Cubana Med Trop. 63: 135-40. PMID: 23437521
    7. Insertion of a short human immunodeficiency virus (HIV)-2 gp36 sequence into an HIV-1 p24 recombinant protein results in a polypeptide with potent and TCRBV-restricted T cell triggering activity.  |  Imberti, L., et al. 1995. Eur J Immunol. 25: 218-25. PMID: 7843234
    8. Overexpression and purification of a recombinant chimeric HIV type 2/HIV type 1 envelope peptide and application in an accelerated immunobased HIV type 1/2 antibody detection system (AIBS): a new rapid serological screening assay.  |  Ecker, B., et al. 1996. AIDS Res Hum Retroviruses. 12: 1081-91. PMID: 8844013
    9. Strongly enhanced sensitivity of a direct anti-HIV-1/-2 assay in seroconversion by incorporation of HIV p24 ag detection: a new generation vironostika HIV Uni-Form II.  |  van Binsbergen, J., et al. 1998. J Virol Methods. 76: 59-71. PMID: 9923740

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    HIV-2 gp36 Antibody (3B10/G2)

    sc-52421
    100 µg/ml
    $316.00