Anti-HIV-1 Tat-SF1 Antibody (C-4) is a mouse monoclonal IgG2b (kappa light chain) HIV-1 Tat-SF1 antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 1-23 at the N-terminus of HIV-1 Tat-SF1 of mouse origin
Anti-HIV-1 Tat-SF1 Antibody (C-4) is recommended for detection of HIV-1 Tat-SF1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-HIV-1 Tat-SF1 Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
blocking peptide, sc-514351 P
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of HIV-1 Tat-SF1 (C-4): sc-514351.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
HIV-1 Tat-SF1 Antibody (C-4) is a high quality monoclonal HIV-1 Tat-SF1 antibody (also designated HIV-1 Tat-SF1 antibody) suitable for the detection of the HIV-1 Tat-SF1 protein of mouse, rat and human origin. HIV-1 Tat-SF1 Antibody (C-4) is available as both the non-conjugated anti-HIV-1 Tat-SF1 antibody form, as well as multiple conjugated forms of anti-HIV-1 Tat-SF1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. HIV-1 Tat-SF1 (HIV-1 Tat-specific factor 1) is a phosphoprotein that plays a role in the process of transcriptional elongation. It is ubiquitously expressed and localizes to the nucleus. HIV-1 Tat-SF1 interacts with Tat, P-TEFb, TFIIF RAP 30, CA150, Spt5, Pol II and U snRNPs. It is structurally similar to CUS2 in yeast. HIV-1 Tat-SF1 contains an acidic C-terminal motif and two RNA recognition motif (RRM) domains that mediate its interaction with U snRNPs. HIV-1 Tat-SF1 forms a complex with U snRNP, thereby coupling transcription and splicing. HIV-1 Tat-SF1 expression is upregulated by the HIV-1 proteins Nef and gp120. It acts as a cofactor for the Tat-enhanced transcription of HIV-1 and is required, along with SPT5, for the activation of Tat. Overexpression of Tat-SF1 and SPT5 stimulates the transcriptional activity of Tat.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences