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HIV- RT Antibody (AS35) is a mouse monoclonal IgG1 antibody that detects HIV- RT protein through immunoprecipitation (IP). Anti-HIV- RT antibody (AS35) is available in non-conjugated format. The reverse transcriptase (RT) enzyme plays a crucial role in retrovirus life cycles, including HIV-1, by converting single-stranded RNA into double-stranded DNA for host cell genome integration. This process enables viral replication and persistence within hosts, making RT an important therapeutic target. HIV-1 reverse transcriptase functions as a heterodimer with p66 and p51 subunits, facilitating viral RNA genome transcription. RT′s structure contains specific domains for RNA binding, DNA synthesis, and proofreading activities. Understanding HIV-1 RT structural details supports both inhibitor development and deeper insights into viral mechanisms, advancing HIV infection treatment strategies.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIV- RT Antibody (AS35) | sc-52768 | 100 µg/ml | $316.00 |