HIV-1 RT Antibody (AS34): sc-52767

HIV-1 RT Antibody (AS34) is a mouse monoclonal IgG1 antibody that detects HIV-1 RT in HIV-1 by immunoprecipitation (IP). HIV-1 reverse transcriptase (RT) is a crucial enzyme that facilitates the conversion of viral single-stranded RNA genome into double-stranded DNA, a process essential for viral genetic material integration into host cell chromosomes. HIV-1 RT operates as a heterodimer, composed of two subunits, which enhances stability and functionality during transcription. HIV-1 RT utilizes host cell tRNA as a primer for DNA synthesis, allowing viral hijacking of cellular machinery for replication. Understanding HIV-1 RT structure and function remains vital for developing antiretroviral therapies, as inhibitors targeting this enzyme, including nucleoside analogues and non-nucleoside reverse transcriptase inhibitors, have proven instrumental in managing HIV infections. Anti-HIV-1 RT antibody (AS34) serves as an invaluable tool for researchers studying HIV replication mechanisms and therapeutic intervention efficacy.

The preferred HIV-1 RT antibody is HIV-1 RT Antibody (39/4.12.2): sc-57829.