HIV-1 p24 Antibody (YDHIV1gp24) is a mouse monoclonal IgG1 antibody that specifically detects HIV-1 p24 in HIV-1 through enzyme-linked immunosorbent assay (ELISA). HIV-1 p24 monoclonal antibody (YDHIV1gp24) recognizes a crucial viral protein encoded by the HIV-1 GAG gene, playing a vital role in viral structural integrity. HIV-1 p24 forms the viral capsid, which protects viral RNA and enzymes during infection while facilitating viral genome delivery into host cells, making HIV-1 p24 (YDHIV1gp24) antibody a key target for therapeutic interventions. Understanding p24′s structure and function remains important for developing vaccines and treatments against HIV, as p24 is a primary viral component that elicits an immune response. Anti-HIV-1 p24 antibody (YDHIV1gp24) serves as an invaluable tool for researchers studying HIV-1, enabling detection and quantification of this critical protein in various experimental settings.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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HIV-1 p24 Antibody (YDHIV1gp24) References:
- Mapping of linear B-cell epitopes on the major core protein p24 of human immunodeficiency virus type 1 (HIV-1). | Kusk, P., et al. 1992. AIDS Res Hum Retroviruses. 8: 1789-94. PMID: 1280956
- Optimized virus disruption improves detection of HIV-1 p24 in particles and uncovers a p24 reactivity in patients with undetectable HIV-1 RNA under long-term HAART. | Schüpbach, J., et al. 2006. J Med Virol. 78: 1003-10. PMID: 16789014
- Detection of p24 in HIV-1 infected cells embedded in LR White and Lowicryl K4M. | Stransky, G., et al. 1991. Histochem J. 23: 381-4. PMID: 1917566
- Prevalence of human immunodeficiency virus type 1 p24 antigen in U.S. blood donors--an assessment of the efficacy of testing in donor screening. The HIV-Antigen Study Group. | Alter, HJ., et al. 1990. N Engl J Med. 323: 1312-7. PMID: 2120589
- The cyclosporin A washout assay to detect HIV-1 uncoating in infected cells. | Hulme, AE. and Hope, TJ. 2014. Methods Mol Biol. 1087: 37-46. PMID: 24158812
- Discrepant amplification results during the development of an assay leads to reclassification of two AIDS reagent repository HIV-2 isolates as HIV-1. | Jagodzinski, LL., et al. 2014. PLoS One. 9: e96554. PMID: 24797800
- Super-rapid quantitation of the production of HIV-1 harboring a luminescent peptide tag. | Ozono, S., et al. 2020. J Biol Chem. 295: 13023-13030. PMID: 32719008
- Assessment of antiretroviral therapy by plasma viral load testing: standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared. | Kappes, JC., et al. 1995. J Acquir Immune Defic Syndr Hum Retrovirol. 10: 139-49. PMID: 7552477
- HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients. | Fackler, OT., et al. 1998. AIDS. 12: 139-46. PMID: 9468362
- Differences in reverse transcriptase activity versus p24 antigen detection in cell culture, when comparing a homogeneous group of HIV type 1 subtype B viruses with a heterogeneous group of divergent strains. | Corrigan, GE., et al. 1998. AIDS Res Hum Retroviruses. 14: 347-52. PMID: 9519896