Date published: 2025-10-15

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HIV-1 p24 Antibody (YDHIV1gp24): sc-73300

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Datasheets
  • HIV-1 p24 Antibody (YDHIV1gp24) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
  • raised against recombinant p24 of HIV-1 origin
  • recommended for detection of Gag p24 of HIV-1 origin by ELISA
  • See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-1 p24 Antibody (YDHIV1gp24). This work is in progress.

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HIV-1 p24 Antibody (YDHIV1gp24) is a mouse monoclonal IgG1 antibody that specifically detects HIV-1 p24 in HIV-1 through enzyme-linked immunosorbent assay (ELISA). HIV-1 p24 monoclonal antibody (YDHIV1gp24) recognizes a crucial viral protein encoded by the HIV-1 GAG gene, playing a vital role in viral structural integrity. HIV-1 p24 forms the viral capsid, which protects viral RNA and enzymes during infection while facilitating viral genome delivery into host cells, making HIV-1 p24 (YDHIV1gp24) antibody a key target for therapeutic interventions. Understanding p24′s structure and function remains important for developing vaccines and treatments against HIV, as p24 is a primary viral component that elicits an immune response. Anti-HIV-1 p24 antibody (YDHIV1gp24) serves as an invaluable tool for researchers studying HIV-1, enabling detection and quantification of this critical protein in various experimental settings.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

HIV-1 p24 Antibody (YDHIV1gp24) References:

  1. Mapping of linear B-cell epitopes on the major core protein p24 of human immunodeficiency virus type 1 (HIV-1).  |  Kusk, P., et al. 1992. AIDS Res Hum Retroviruses. 8: 1789-94. PMID: 1280956
  2. Optimized virus disruption improves detection of HIV-1 p24 in particles and uncovers a p24 reactivity in patients with undetectable HIV-1 RNA under long-term HAART.  |  Schüpbach, J., et al. 2006. J Med Virol. 78: 1003-10. PMID: 16789014
  3. Detection of p24 in HIV-1 infected cells embedded in LR White and Lowicryl K4M.  |  Stransky, G., et al. 1991. Histochem J. 23: 381-4. PMID: 1917566
  4. Prevalence of human immunodeficiency virus type 1 p24 antigen in U.S. blood donors--an assessment of the efficacy of testing in donor screening. The HIV-Antigen Study Group.  |  Alter, HJ., et al. 1990. N Engl J Med. 323: 1312-7. PMID: 2120589
  5. The cyclosporin A washout assay to detect HIV-1 uncoating in infected cells.  |  Hulme, AE. and Hope, TJ. 2014. Methods Mol Biol. 1087: 37-46. PMID: 24158812
  6. Discrepant amplification results during the development of an assay leads to reclassification of two AIDS reagent repository HIV-2 isolates as HIV-1.  |  Jagodzinski, LL., et al. 2014. PLoS One. 9: e96554. PMID: 24797800
  7. Super-rapid quantitation of the production of HIV-1 harboring a luminescent peptide tag.  |  Ozono, S., et al. 2020. J Biol Chem. 295: 13023-13030. PMID: 32719008
  8. Assessment of antiretroviral therapy by plasma viral load testing: standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared.  |  Kappes, JC., et al. 1995. J Acquir Immune Defic Syndr Hum Retrovirol. 10: 139-49. PMID: 7552477
  9. HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients.  |  Fackler, OT., et al. 1998. AIDS. 12: 139-46. PMID: 9468362
  10. Differences in reverse transcriptase activity versus p24 antigen detection in cell culture, when comparing a homogeneous group of HIV type 1 subtype B viruses with a heterogeneous group of divergent strains.  |  Corrigan, GE., et al. 1998. AIDS Res Hum Retroviruses. 14: 347-52. PMID: 9519896

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

HIV-1 p24 Antibody (YDHIV1gp24)

sc-73300
100 µg/ml
$316.00