Date published: 2025-10-15

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HIV-1 p24 Antibody (5): sc-130531

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Datasheets
  • HIV-1 p24 Antibody (5) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 100 µg/ml
  • raised against recombinant p24 protein of HIV-1 origin with epitope mapping to amino acids 48-62
  • recommended for detection of Gag p24 of HIV-1 origin by WB, IF and IHC(P)
  • See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-1 p24 Antibody (5). This work is in progress.

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HIV-1 p24 Antibody (5) is a mouse monoclonal IgG2a antibody that detects HIV-1 p24 by western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Anti-HIV-1 p24 antibody (5) plays a crucial role in the study of HIV-1, as p24 is a key structural protein that forms the viral capsid, which is essential for the protection and delivery of the viral genome into host cells. HIV-1 p24 monoclonal antibody (5) enables detection of capsid integrity, which is vital for viral infection and replication within the host, making p24 a significant target for both diagnostic and therapeutic strategies against HIV. Understanding the structure of p24 and its interactions with host cell machinery can provide insights into viral pathogenesis and the development of effective antiviral therapies. HIV-1 p24 (5) antibody helps researchers effectively monitor p24 levels in various experimental settings, contributing to a deeper understanding of HIV-1 biology and the immune response to infection.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

HIV-1 p24 Antibody (5) References:

  1. p24 Antigen detection assay modified with a booster step for diagnosis and monitoring of human immunodeficiency virus type 1 infection.  |  Sutthent, R., et al. 2003. J Clin Microbiol. 41: 1016-22. PMID: 12624024
  2. Cocaine amplifies HIV-1 replication in cytomegalovirus-stimulated peripheral blood mononuclear cell cocultures.  |  Peterson, PK., et al. 1992. J Immunol. 149: 676-80. PMID: 1320643
  3. HIV type 1 that select tRNA(His) or tRNA(Lys1,2) as primers for reverse transcription exhibit different infectivities in peripheral blood mononuclear cells.  |  Moore, KL., et al. 2004. AIDS Res Hum Retroviruses. 20: 373-81. PMID: 15157356
  4. A simple competitive RT-PCR assay for quantitation of HIV-1 subtype B and non-B RNA in plasma.  |  Hamatake, M., et al. 2007. J Virol Methods. 142: 113-7. PMID: 17367872
  5. The effect of fresh lymphocytes on increased sensitivity of HIV-1 isolation: a multicenter study.  |  Farzadegan, H., et al. 1990. J Acquir Immune Defic Syndr (1988). 3: 981-6. PMID: 2118952
  6. Complete and repeatable inactivation of HIV-1 viral particles in suspension using a photo-labeled non-nucleoside reverse transcriptase inhibitor.  |  Marin-Muller, C., et al. 2013. J Virol Methods. 189: 125-8. PMID: 23384676
  7. Failure of fourth-generation enzyme immunoassay in HIV screening and plasma HIV-1 RNA detection in recent high-risk behavior.  |  Maylin, S., et al. 2014. Intervirology. 57: 49-51. PMID: 24157685
  8. The Molecular Characterization of Intestinal Explant HIV Infection Using Polymerase Chain Reaction-Based Techniques.  |  Janocko, L., et al. 2015. AIDS Res Hum Retroviruses. 31: 981-91. PMID: 26214703
  9. Immune complex-dissociated p24 antigen in congenital or perinatal HIV infection: role in the diagnosis and assessment of risk of infection in infants.  |  Rich, KC., et al. 1997. J Acquir Immune Defic Syndr Hum Retrovirol. 15: 198-203. PMID: 9257654

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

HIV-1 p24 Antibody (5)

sc-130531
100 µg/ml
$316.00