Date published: 2025-10-15

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HIV-1 p24 Antibody (05-009): sc-65924

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Datasheets
  • HIV-1 p24 Antibody (05-009) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against amino acids 80-90 of p24 of HIV-1 origin
  • recommended for detection of Gag p24 of HIV-1 origin by WB
  • See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-1 p24 Antibody (05-009). This work is in progress.

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    HIV-1 p24 Antibody (05-009) is a mouse monoclonal IgG1 antibody that detects p24 protein of HIV-1 by western blotting (WB). Anti-p24 antibody (05-009) plays a crucial role in the study of human immunodeficiency virus (HIV), a retrovirus responsible for acquired immune deficiency syndrome (AIDS), which severely compromises the immune system and leads to life-threatening infections. The p24 protein, encoded by the HIV-1 gag gene, is essential for the structural integrity of the virus, as p24 forms the viral capsid that encases the viral RNA and proteins, thereby protecting them during the viral life cycle. Understanding p24 structure is vital, as p24 not only contributes to the stability of the virus but also serves as a target for diagnostic assays and therapeutic interventions. p24 monoclonal antibody (05-009) specifically recognizes this protein, allowing researchers to monitor viral load and study the dynamics of HIV infection, making p24 (05-009) antibody an invaluable tool in both clinical and research settings.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    HIV-1 p24 Antibody (05-009) References:

    1. HIV-1 p24 vaccine protects cats against feline immunodeficiency virus infection.  |  Coleman, JK., et al. 2005. AIDS. 19: 1457-66. PMID: 16135898
    2. Adaptation of the ultrasensitive HIV-1 p24 antigen assay to dried blood spot testing.  |  Knuchel, MC., et al. 2007. J Acquir Immune Defic Syndr. 44: 247-53. PMID: 17146373
    3. Rapid detection of HIV-1 p24 antigen using magnetic immuno-chromatography (MICT).  |  Workman, S., et al. 2009. J Virol Methods. 160: 14-21. PMID: 19482361
    4. Enhanced Sensitivity for Detection of HIV-1 p24 Antigen by a Novel Nuclease-Linked Fluorescence Oligonucleotide Assay.  |  Fan, P., et al. 2015. PLoS One. 10: e0125701. PMID: 25915630
    5. Increased Sensitivity of HIV-1 p24 ELISA Using a Photochemical Signal Amplification System.  |  Bystryak, S. and Santockyte, R. 2015. J Acquir Immune Defic Syndr. 70: 109-14. PMID: 26090753
    6. Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-cell responses.  |  Tan, HX., et al. 2016. Vaccine. 34: 1172-9. PMID: 26826545
    7. Detection of HIV-1 p24 antigen in patients with varying degrees of viremia using an ELISA with a photochemical signal amplification system.  |  Bystryak, S. and Acharya, C. 2016. Clin Chim Acta. 456: 128-136. PMID: 26940950
    8. HIV-1 p24 and CD4+ T cell count during boosted protease-inhibitor monotherapy in HIV-infected patients.  |  Benmarzouk-Hidalgo, OJ., et al. 2017. Enferm Infecc Microbiol Clin. 35: 174-178. PMID: 26976380
    9. In Silico Design and Immunologic Evaluation of HIV-1 p24-Nef Fusion Protein to Approach a Therapeutic Vaccine Candidate.  |  Larijani, MS., et al. 2018. Curr HIV Res. 16: 322-337. PMID: 30605062
    10. Surface Plasmon Resonance Assay for Label-Free and Selective Detection of HIV-1 p24 Protein.  |  Sarcina, L., et al. 2021. Biosensors (Basel). 11: PMID: 34204930

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    HIV-1 p24 Antibody (05-009)

    sc-65924
    100 µg/ml
    $316.00