HIV-1 p24 Antibody (05-001): sc-65918
- HIV-1 p24 Antibody (05-001) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant p24 protein of HIV-1 origin with epitope mapping to amino acids 48-62
- recommended for detection of Gag p24 of HIV-1 origin and Nef of HIV-1 subtypes A, B and C origin by WB, IF and IHC(P)
- See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HIV-1 p24 Antibody (05-001). This work is in progress.
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HIV-1 p24 Antibody (05-001) is a mouse monoclonal IgG2a antibody that detects p24 protein by western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-p24 antibody (05-001) plays a crucial role in studying human immunodeficiency virus (HIV), particularly in understanding the structure and function of the viral capsid, which is primarily composed of p24 protein. The capsid is essential for protecting viral RNA and enzymes during the virus′s life cycle, facilitating the delivery of genetic material into host cells. The integrity of the capsid is vital for viral ability to infect host cells and replicate, making p24 a key target for both diagnostic and therapeutic strategies against HIV. By utilizing p24 monoclonal antibody (05-001), researchers can effectively monitor p24 levels, providing insights into viral load and the progression of HIV infection, which is critical for developing effective treatments and interventions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HIV-1 p24 Antibody (05-001) References:
- HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice. | Kulkarni, V., et al. 2013. PLoS One. 8: e60245. PMID: 23555935
- Endotoxin-minimized HIV-1 p24 fused to murine hsp70 activates dendritic cells, facilitates endocytosis and p24-specific Th1 response in mice. | Krupka, M., et al. 2015. Immunol Lett. 166: 36-44. PMID: 26021827
- Detection of HIV-1 p24 at Attomole Level by Ultrasensitive ELISA with Thio-NAD Cycling. | Nakatsuma, A., et al. 2015. PLoS One. 10: e0131319. PMID: 26098695
- Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents. | Passaes, CPB., et al. 2017. J Virol. 91: PMID: 28077644
- Ultra-low HIV-1 p24 detection limits with a bioelectronic sensor. | Macchia, E., et al. 2020. Anal Bioanal Chem. 412: 811-818. PMID: 31865415
- Production of Recombinant HIV-1 p24-Nef Protein in Two Forms as Potential Candidate Vaccines in Three Vehicles. | Larijani, MS., et al. 2020. Curr Drug Deliv. 17: 387-395. PMID: 32183667
- HIV-1 p24-nef DNA Vaccine Plus Protein Boost Expands T-Cell Responses in BALB/c. | Larijani, MS., et al. 2021. Curr Drug Deliv. 18: 1014-1021. PMID: 33388019
- Evaluation of transduced dendritic cells expressing HIV-1 p24-Nef antigens in HIV-specific cytotoxic T cells induction as a therapeutic candidate vaccine. | Sadat Larijani, M., et al. 2021. Virus Res. 298: 198403. PMID: 33775753
- Fluorescence and visual immunoassay of HIV-1 p24 antigen in clinical samples via multiple selective recognitions of CdTe QDs. | Tang, Z., et al. 2021. Mikrochim Acta. 188: 422. PMID: 34791532
- A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples. | Wei, X., et al. 2022. Nat Commun. 13: 6852. PMID: 36369146
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIV-1 p24 Antibody (05-001) | sc-65918 | 100 µg/ml | $316.00 |