HIP2 Antibody (C-5): sc-390138
- HIP2 Antibody (C-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-100 mapping at the N-terminus of HIP2 of human origin
- recommended for detection of HIP2 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HIP2 Antibody (C-5) for WB applications. These reagents are now offered in bundles with HIP2 Antibody (C-5) (see ordering information below).
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HIP2 Antibody (C-5) is a mouse monoclonal IgG1 antibody that detects HIP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HIP2, or Huntingtin interacting protein 2, is a crucial membrane-associated protein that interacts specifically with the N-terminus of the Huntingtin protein, playing a significant role in cellular processes. Anti-HIP2 antibody (C-5) recognizes structural characteristics, particularly HIP2′s ability to form a complex with Huntingtin, which is essential for maintaining cellular integrity and function. This interaction is vital for proper trafficking of proteins and regulation of cytoskeletal dynamics, which are critical for neuronal health. Disruption of the HIP2-Huntingtin interaction can lead to cellular dysfunction and is implicated in the pathogenesis of Huntington′s disease, highlighting the necessity of studying this protein for understanding neurodegenerative disorders. HIP2 monoclonal antibody (C-5) provides a reliable tool for researchers investigating the molecular mechanisms underlying Huntington′s disease and other related conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIP2 Antibody (C-5) | sc-390138 | 200 µg/ml | $322.00 | |||
HIP2 Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-540762 | 200 µg Ab; 10 µg BP | $361.00 | |||
HIP2 Antibody (C-5): m-IgG1 BP-HRP Bundle | sc-542354 | 200 µg Ab; 20 µg BP | $361.00 |