HHV-6 gp82/105 Antibody (2D6): sc-65448

HHV-6 gp82/105 Antibody (2D6) is a mouse monoclonal IgG2b kappa light chain antibody that detects the late protein gp82/gp105 of strain A of HHV-6 origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-gp82/105 antibody (2D6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. gp82/gp105 plays a crucial role in viral lifecycle, particularly in viral entry into host cells, which is essential for infection establishment and viral replication. Understanding gp82/gp105 function provides insights into HHV-6 pathogenesis and potential links to various diseases, including neurological disorders. The Herpesviridae family, to which HHV-6 belongs, consists of DNA viruses causing significant health issues in humans and other animals. Among eight distinct viruses in this family, HHV-6 is particularly noteworthy due to its association with febrile illnesses and potential role in demyelinating diseases such as multiple sclerosis. HHV-6 persistence and latency in various tissues, including monocytes/macrophages, salivary glands, brain, and kidney, highlight the importance of studying gp82/gp105 for understanding viral impact on human health.

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HHV-6 gp82/105 Antibody (2D6) References:

1. The HHV6 paradox: ubiquitous commensal or insidious pathogen? A two-step in situ PCR approach.  |  Blumberg, BM., et al. 2000. J Clin Virol. 16: 159-78. PMID: 10738136
2. Human herpesvirus 6 (HHV6) infection.  |  Abdel-Haq, NM. and Asmar, BI. 2004. Indian J Pediatr. 71: 89-96. PMID: 14979393
3. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children.  |  Caserta, MT., et al. 2004. J Pediatr. 145: 478-84. PMID: 15480370
4. Lack of association of polyomavirus and herpesvirus types 6 and 7 in human lymphomas.  |  Hernández-Losa, J., et al. 2005. Cancer. 103: 293-8. PMID: 15593086
5. Fatal pulmonary failure attributable to viral pneumonia with human herpes virus 6 (HHV6) in a young immunocompetent woman.  |  Merk, J., et al. 2005. J Intensive Care Med. 20: 302-6. PMID: 16206417
6. [Drug hypersensitivity syndrome associated with a primary HHV6 infection].  |  Debarbieux, S., et al. 2006. Ann Dermatol Venereol. 133: 145-7. PMID: 16508598
7. Human herpesvirus 6 (HHV6) and chronic fatigue syndrome (CFS).  |  Ablashi, DV., et al. 1991. Can Dis Wkly Rep. 17 Suppl 1E: 33-40. PMID: 1669351
8. Three new human herpesviruses (HHV6, 7, and 8).  |  Levy, JA. 1997. Lancet. 349: 558-63. PMID: 9048803
9. The latency rate of human herpesvirus 6 (HHV6) in positive and negative human immunodeficiency virus (HIV) infection of intravenous drug users (IVDU).  |  Jayavasu, C., et al. 1997. Asian Pac J Allergy Immunol. 15: 29-33. PMID: 9251845

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HHV-6 gp82/105 Antibody (2D6) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HHV-6 gp82/105 Antibody (2D6) Specifications

Alternate Product Name: HHV-6 gp82/105

Product Clone Name: 2D6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: strain A

Epitope Species: HHV-6

Product Reactivity/Detection: late protein gp82/gp105

Species Reactivity/Detection: strain A of HHV-6

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: strain A of HHV-6

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for HHV-6 gp82/105 Antibody (2D6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin