HELIC2 Antibody (B-11): sc-393517
- HELIC2 Antibody (B-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of HELIC2 of human origin
- recommended for detection of HELIC2 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HELIC2 Antibody (B-11) for WB applications. These reagents are now offered in bundles with HELIC2 Antibody (B-11) (see ordering information below).
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HELIC2 Antibody (B-11) is a mouse monoclonal IgG2b antibody that detects HELIC2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HELIC2, also known as SNRNP200, ASCC3L1, or BRR2, is a 2,136 amino acid protein that plays a crucial role as an RNA helicase, facilitating specific RNA-RNA conformational changes essential for the second step of RNA splicing. This process is vital for the proper maturation of mRNA, which ultimately influences gene expression and cellular function. HELIC2 is localized in the nucleus, where HELIC2 interacts with various RNA molecules and spliceosomal components, underscoring HELIC2′s importance in the regulation of gene expression and the maintenance of cellular homeostasis. HELIC2 exists in multiple alternatively spliced isoforms, which may contribute to HELIC2′s functional diversity and adaptability in different cellular contexts. The gene encoding HELIC2 is located on human chromosome 2, a region that is home to over 1,400 genes and is implicated in various genetic disorders, highlighting HELIC2′s significance in both normal physiology and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HELIC2 Antibody (B-11) | sc-393517 | 200 µg/ml | $322.00 | |||
HELIC2 Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-535807 | 200 µg Ab; 40 µg BP | $361.00 | |||
HELIC2 Antibody (B-11): m-IgG2b BP-HRP Bundle | sc-549480 | 200 µg Ab; 10 µg BP | $361.00 |