HDHD2 Antibody (C-1): sc-514621
- HDHD2 Antibody (C-1) is a mouse monoclonal IgG1 κ HDHD2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 235-256 at the C-terminus of HDHD2 of human origin
- HDHD2 Antibody (C-1) is recommended for detection of HDHD2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-HDHD2 Antibody (C-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HDHD2 Antibody (C-1) for WB applications. These reagents are now offered in bundles with HDHD2 Antibody (C-1) (see ordering information below).
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HDHD2 Antibody (C-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects HDHD2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HDHD2 (C-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HDHD2 protein, also known as haloacid dehalogenase-like hydrolase domain containing 2, consists of 259 amino acids and is expressed in two isoforms due to alternative splicing. HDHD2 plays a crucial role in the hydrolytic dehalogenation of D- and L-2-haloalkanoic acids, which is essential for the metabolism of halogenated compounds and the detoxification of environmental pollutants. HDHD2 enzymatic activity is attributed to two active sites, which include an L-2-haloacid dehalogenase and a carboxylate group, allowing conversion of harmful substances into less toxic forms. HDHD2 gene is located on human chromosome 18, and deletions in this region can lead to various health issues, including deafness and blindness, as well as conditions such as Trisomy 18 and Niemann-Pick disease. HDHD2′s ability to interact with other proteins involved in metabolic pathways further underscores its importance in cellular function and disease processes, making anti-HDHD2 antibody (C-1) a valuable tool for researchers studying these critical biological mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HDHD2 Antibody (C-1) References:
- Chromosome 18 aberrations and epilepsy: a review. | Grosso, S., et al. 2005. Am J Med Genet A. 134A: 88-94. PMID: 15690352
- Cognitive ability predicts degree of genetic abnormality in participants with 18q deletions. | Semrud-Clikeman, M., et al. 2005. J Int Neuropsychol Soc. 11: 584-90. PMID: 16212685
- Detection of hypothetical proteins in human fetal perireticular nucleus. | Hepner, F., et al. 2005. J Proteome Res. 4: 2379-85. PMID: 16335990
- Autosomal dominant nonsyndromic cleft lip and palate: significant evidence of linkage at 18q21.1. | Beiraghi, S., et al. 2007. Am J Hum Genet. 81: 180-8. PMID: 17564975
- Delineation of a critical region on chromosome 18 for the del(18)(q12.2q21.1) syndrome. | Buysse, K., et al. 2008. Am J Med Genet A. 146A: 1330-4. PMID: 18412119
- Direct sequence analysis of 14q+ and 18q- chromosome junctions at the MBR and MCR revealing clustering within the MBR in follicular lymphoma. | Cotter, FE., et al. 1991. Ann Oncol. 2 Suppl 2: 93-7. PMID: 2049326
- Direct sequence analysis of the 14q+ and 18q- chromosome junctions in follicular lymphoma. | Cotter, F., et al. 1990. Blood. 76: 131-5. PMID: 2194586
- Linkage of Niemann-Pick disease type C to human chromosome 18. | Carstea, ED., et al. 1993. Proc Natl Acad Sci U S A. 90: 2002-4. PMID: 8446622
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HDHD2 Antibody (C-1) | sc-514621 | 200 µg/ml | $322.00 | |||
HDHD2 Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-531178 | 200 µg Ab; 10 µg BP | $361.00 | |||
HDHD2 Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-524792 | 200 µg Ab, 40 µg BP | $361.00 | |||
HDHD2 Antibody (C-1): m-IgG1 BP-HRP Bundle | sc-544425 | 200 µg Ab; 20 µg BP | $361.00 | |||
HDHD2 Antibody (C-1) AC | sc-514621 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HDHD2 Antibody (C-1) HRP | sc-514621 HRP | 200 µg/ml | $322.00 | |||
HDHD2 Antibody (C-1) FITC | sc-514621 FITC | 200 µg/ml | $336.00 | |||
HDHD2 Antibody (C-1) PE | sc-514621 PE | 200 µg/ml | $349.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 488 | sc-514621 AF488 | 200 µg/ml | $364.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 546 | sc-514621 AF546 | 200 µg/ml | $364.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 594 | sc-514621 AF594 | 200 µg/ml | $364.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 647 | sc-514621 AF647 | 200 µg/ml | $364.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 680 | sc-514621 AF680 | 200 µg/ml | $364.00 | |||
HDHD2 Antibody (C-1) Alexa Fluor® 790 | sc-514621 AF790 | 200 µg/ml | $364.00 | |||
HDHD2 (C-1) Neutralizing Peptide | sc-514621 P | 100 µg/0.5 ml | $69.00 |