HDGF Antibody (H-3): sc-398344
- HDGF Antibody (H-3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 121-168 mapping within an internal region of HDGF of human origin
- recommended for detection of HDGF of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG1 BP-HRP is the preferred secondary detection reagent for HDGF Antibody (H-3) for WB applications. This reagent is now offered in a bundle with HDGF Antibody (H-3) (see ordering information below).
HDGF Antibody (H-3) is a mouse monoclonal IgG1 antibody that detects Hepatoma Derived Growth Factor (HDGF) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HDGF plays a significant role in various biological processes, particularly in cell proliferation and tissue remodeling. HDGF is primarily located in the nucleus and cytoplasm of smooth muscle and endothelial cells, where HDGF expression is vital for organ development and response to injury. HDGF presence in these cellular compartments underscores HDGF′s importance in regulating vascular smooth muscle cell growth and facilitating lung epithelial cell proliferation during lung injury recovery. HDGF is a heparin-binding protein highly expressed in tumor cells, where HDGF acts as a mitogen, stimulating cell division and contributing to tumor progression. Understanding HDGF localization and function is essential for elucidating HDGF′s role in both normal physiological processes and pathological conditions, making anti-HDGF antibody (H-3) an invaluable tool for researchers studying cancer biology and tissue regeneration.
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HDGF Antibody (H-3) References:
- Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer. | Zhou, Y., et al. 2010. Diagn Pathol. 5: 58. PMID: 20846397
- p53 negatively regulates the hepatoma growth factor HDGF. | Sasaki, Y., et al. 2011. Cancer Res. 71: 7038-47. PMID: 22006999
- HDGF and ADAM9 are novel molecular staging biomarkers, prognostic biomarkers and predictive biomarkers for adjuvant chemotherapy in surgically resected stage I non-small cell lung cancer. | Zhang, J., et al. 2014. J Cancer Res Clin Oncol. 140: 1441-9. PMID: 24770635
- A complex mechanism for HDGF-mediated cell growth, migration, invasion, and TMZ chemosensitivity in glioma. | Song, Y., et al. 2014. J Neurooncol. 119: 285-95. PMID: 24986090
- Downregulation of the expression of HDGF attenuates malignant biological behaviors of hilar cholangiocarcinoma cells. | Liu, Y., et al. 2015. Mol Med Rep. 12: 4713-4719. PMID: 26081074
- High Serum HDGF Levels Are Predictive of Bone Metastasis and Unfavorable Prognosis in Non-Small Cell Lung Cancer. | Zhang, G., et al. 2017. Tohoku J Exp Med. 242: 101-108. PMID: 28592712
- A novel HDGF-ALCAM axis promotes the metastasis of Ewing sarcoma via regulating the GTPases signaling pathway. | Yang, Y., et al. 2021. Oncogene. 40: 731-745. PMID: 33239755
- NAP1L1 promotes tumor proliferation through HDGF/C-JUN signaling in ovarian cancer. | Xiaohua Zhu,., et al. 2022. BMC Cancer. 22: 339. PMID: 35351053
- lncRNA DLG1-AS1 promotes cervical cancer cell gemcitabine resistance by regulating miR-16-5p/HDGF. | Zou, MJ., et al. 2022. J Obstet Gynaecol Res. 48: 1836-1847. PMID: 35388952
- Extracellular vesicle proteomic analysis leads to the discovery of HDGF as a new factor in multiple myeloma biology. | Hoelzinger, DB., et al. 2022. Blood Adv. 6: 3458-3471. PMID: 35395072
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HDGF Antibody (H-3) | sc-398344 | 200 µg/ml | $322.00 | |||
HDGF Antibody (H-3): m-IgG1 BP-HRP Bundle | sc-542712 | 200 µg Ab; 20 µg BP | $361.00 |