HDAC3 CRISPR Plasmids (h) human HDAC3-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

HDAC3 CRISPR Plasmids (h)

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Datasheets

    • Target species: human; for corresponding mouse product, see HDAC3 CRISPR Plasmids (m)
    • CRISPR/Cas9 KO Plasmids consists of HDAC3-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library
    • For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA
    • Target-specific CRISPR Plasmids for both gene knockout and activation are available. Please refer to the detailed product information in the tabs below
    • Gene knockdown or activation can be assayed using HDAC3 Antibody (A-3): sc-376957
    • All products are provided as transfection-ready, purified plasmid DNA, except the Lentiviral Activation Particles which have been prepackaged as Lentiviral Particles for use with hard-to-transfect cells
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Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
HumanHDAC388415q31.3XM_011537697, NM_003883O15379605166

Hi I want to KO human HDAC3 gene via CRISPR approach. I would like to know the difference between HDAC3 Double Nickase Plasmid (h) vs HDAC Double Nickase Plasmid (h2). Pls let me know. Thanks.

Asked by: Sushil
Thank you for your question. The HDAC3 Double Nickase Plasmid (h) only differs from the HDAC Double Nickase Plasmid (h2) in the location of the gRNA used. The only difference is the gRNA sequence, so you can use either one for knockout of the HDAC3 gene. You can read more about our CRISPR reagents here: https://www.scbt.com/whats-new/crispr-systems Feel free to reach out to Technical Service if you have any further questions or need assistance with your CRISPR project.
Answered by: Tech Service
Date published: 2019-10-28
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