HDAC11 CRISPR Plasmids (h) human HDAC11-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

HDAC11 CRISPR Plasmids (h)

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Datasheets

    • Target species: human; for corresponding mouse product, see HDAC11 CRISPR Plasmids (m)
    • CRISPR/Cas9 KO Plasmids consists of HDAC11-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library
    • For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA
    • Target-specific CRISPR Plasmids for both gene knockout and activation are available. Please refer to the detailed product information in the tabs below
    • Gene knockdown or activation can be assayed using HDAC11 Antibody (C-5): sc-390737
    • All products are provided as transfection-ready, purified plasmid DNA, except the Lentiviral Activation Particles which have been prepackaged as Lentiviral Particles for use with hard-to-transfect cells
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Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
HumanHDAC11798853p25.1XM_005265491, XM_005265492, XM_006713338, XM_011534131, XM_011534132, XM_011534135, XM_017007234, NM_001136041, NM_001330636, NM_024827Q96DB2607226

Hi, I have one question about lentiviral activation particles. And, this viral particle would be just for one-time use, right? :)

Asked by: ssssssssssian
Thank you for your question. Yes, the CRISPR Cas9 Activation particles will give you increased expression of your target gene. It is not a permanent unregulation, but it will last a few generations as long as your cells retain all 3 plasmids necessary for triggering transcription. There is enough for up to 20 transfections.
Answered by: Tech Service
Date published: 2019-09-16
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