CD44 Antibody (P2A1): sc-53298
- CD44 Antibody (P2A1) is a mouse monoclonal IgG2a κ, cited in 8 publications, provided at 200 µg/ml
- raised against ocular melanoma cell line (V+B2)
- recommended for detection of HCAM of human origin by WB, IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD44 Antibody (P2A1) for WB and IHC(P) applications. These reagents are now offered in bundles with CD44 Antibody (P2A1) (see ordering information below).
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SEE ALSO...
HCAM Antibody (P2A1) is a mouse monoclonal IgG2a antibody that detects HCAM in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM functions as a receptor for hyaluronic acid (HA) and interacts with ligands such as osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. HCAM′s structure features a Link domain, which is essential for binding capabilities and functional versatility. HCAM undergoes alternative splicing, resulting in multiple isoforms, including CD44R, CDw44, CD44S, CD44H, and CD44E, with CD44H being particularly prominent in cancer tissues. High expression levels in tumors suggest HCAM, especially CD44H variant, may play a pivotal role in tumor progression and could serve as a potential biomarker for cancer diagnosis and treatment strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (P2A1) | sc-53298 | 200 µg/ml | $322.00 | |||
CD44 Antibody (P2A1): m-IgG Fc BP-HRP Bundle | sc-536929 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD44 Antibody (P2A1): m-IgGκ BP-HRP Bundle | sc-534104 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD44 Antibody (P2A1): m-IgG2a BP-HRP Bundle | sc-547902 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD44 Antibody (P2A1) FITC | sc-53298 FITC | 200 µg/ml | $336.00 | |||
CD44 Antibody (P2A1) PE | sc-53298 PE | 200 µg/ml | $349.00 |