CD44 Antibody (P1G12): sc-53503
- CD44 Antibody (P1G12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against HT-1080 fibrosarcoma cells of human origin
- recommended for detection of HCAM of human origin by WB, IP and IF
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD44 Antibody (P1G12) for WB applications. These reagents are now offered in bundles with CD44 Antibody (P1G12) (see ordering information below).
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SEE ALSO...
HCAM Antibody (P1G12) is a mouse monoclonal IgG1 antibody that detects HCAM in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM functions primarily as a receptor for hyaluronic acid (HA) and interacts with various ligands, including osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. HCAM′s structure features a Link domain, which is essential for binding capabilities and functional versatility. HCAM undergoes alternative splicing, resulting in multiple isoforms such as CD44R, CDw44, CD44S, CD44H, and CD44E, with CD44H being particularly prominent in cancer tissues. High expression of CD44H in tumors suggests critical involvement in tumor progression, making HCAM a valuable target for research in cancer biology and therapeutic development. Anti-HCAM antibody (P1G12) serves as an essential tool for researchers exploring HCAM′s intricate roles in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (P1G12) | sc-53503 | 200 µg/ml | $322.00 | |||
CD44 Antibody (P1G12): m-IgG Fc BP-HRP Bundle | sc-536976 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD44 Antibody (P1G12): m-IgGκ BP-HRP Bundle | sc-534153 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD44 Antibody (P1G12): m-IgG1 BP-HRP Bundle | sc-544936 | 200 µg Ab; 20 µg BP | $361.00 |