CD44 Antibody (F10-44-2): sc-52535
- CD44 Antibody (F10-44-2) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against HCAM-positive cell preparation of human origin
- recommended for detection of HCAM of human origin by IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD44 Antibody (F10-44-2) for IHC(P) applications. These reagents are now offered in bundles with CD44 Antibody (F10-44-2) (see ordering information below).
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SEE ALSO...
HCAM Antibody (F10-44-2) is a mouse monoclonal IgG2a antibody that detects HCAM in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM functions primarily as a receptor for hyaluronic acid (HA) and interacts with various ligands, including osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. The significance of HCAM′s structure lies in its Link domain, which is essential for binding capabilities and functional versatility. Notably, HCAM undergoes alternative splicing, resulting in multiple isoforms such as CD44R, CDw44, CD44S, CD44H, and CD44E, with CD44H being particularly prominent in cancer tissues. This high expression level in tumors suggests that HCAM, especially CD44H variant, may play a pivotal role in tumor progression and metastasis, making HCAM a critical target for research in cancer biology and therapeutic interventions. Anti-HCAM antibody (F10-44-2) is an invaluable tool for studying the dynamics of cell adhesion and migration in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (F10-44-2) | sc-52535 | 200 µg/ml | $322.00 | |||
CD44 Antibody (F10-44-2): m-IgG Fc BP-HRP Bundle | sc-536858 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD44 Antibody (F10-44-2): m-IgGκ BP-HRP Bundle | sc-534025 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD44 Antibody (F10-44-2): m-IgG2a BP-HRP Bundle | sc-547886 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD44 Antibody (F10-44-2) FITC | sc-52535 FITC | 200 µg/ml | $336.00 | |||
CD44 Antibody (F10-44-2) PE | sc-52535 PE | 200 µg/ml | $349.00 |