GUK1 Antibody (F-3): sc-271385
- GUK1 Antibody (F-3) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 32-108 mapping within an internal region of GUK1 of human origin
- recommended for detection of GUK1 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GUK1 Antibody (F-3). This work is in progress.
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SEE ALSO...
GUK1 Antibody (F-3) is a mouse monoclonal IgG2a antibody that detects GUK1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GUK1, or guanylate kinase 1, is a 197 amino acid protein characterized by a guanylate kinase-like domain, which is crucial for its enzymatic function. GUK1 is primarily located in the cytoplasm, where GUK1 plays a vital role in the recycling of guanine nucleotides by catalyzing the ATP-dependent conversion of GMP to GDP. Proper functioning of GUK1 is essential for maintaining the balance of guanine nucleotides, which are critical for various cellular processes, including signal transduction pathways that regulate cell growth and differentiation. Dysregulation of GUK1 has been linked to the development of pituitary adenocarcinomas, highlighting GUK1′s potential role in tumorigenesis. Anti-GUK1 antibody (F-3) is an invaluable tool for researchers studying the implications of GUK1 in cellular signaling and cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GUK1 Antibody (F-3) | sc-271385 | 200 µg/ml | $322.00 |