GSTP1 Antibody (H-11): sc-376013

GSTP1 Antibody (H-11) is a mouse monoclonal IgG1 antibody that detects Glutathione S-transferase P1 (GSTP1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GSTP1 plays a crucial role in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides, which is vital for cellular protection against oxidative stress. The upregulation of GSTP1 in response to oxidative stress highlights its importance in maintaining cellular homeostasis and preventing damage from reactive oxygen species. Additionally, the GSTP1 gene is subject to CpG island hypermethylation, a modification that has been linked to human prostatic carcinogenesis. This hypermethylation can be detected in biological fluids such as urine, ejaculate, and plasma from men diagnosed with prostate cancer, suggesting that GSTP1 may serve as a valuable biomarker for prostate cancer screening. Anti-GSTP1 antibody (H-11) is therefore an essential tool for researchers investigating the role of GSTP1 in cancer biology and its potential as a diagnostic marker.

The preferred GSTP1 antibody is GSTP1 Antibody (3F2C2): sc-66000.