GST Antibody (S-tag-05): sc-66167

GST Antibody (S-tag-05) is a mouse monoclonal IgG2b antibody that detects glutathione-S-transferase (GST) in non-species reactive (NSR) samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-GST antibody (S-tag-05) is particularly valuable in research involving protein expression and purification, as GST is widely used as a fusion partner in recombinant protein technology. GST plays a crucial role in detoxification processes within cells by catalyzing the conjugation of glutathione to various substrates, which is essential for the elimination of potentially harmful compounds. This function not only aids in cellular protection but also highlights GST′s importance in pharmacology and toxicology, as understanding GST activity can lead to insights into drug metabolism and therapeutic strategy development. GST monoclonal antibody (S-tag-05) specifically recognizes GST fusion proteins, making this tool indispensable for researchers analyzing protein expression levels and interactions in various experimental setups.

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GST Antibody (S-tag-05) References:

1. A common class of nematode glutathione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans.  |  Campbell, AM., et al. 2001. Comp Biochem Physiol B Biochem Mol Biol. 128: 701-8. PMID: 11290452
2. Expression of glutathione S-transferase pi (GST-pi) in human malignant ovarian tumors.  |  Satoh, T., et al. 2001. Eur J Obstet Gynecol Reprod Biol. 96: 202-8. PMID: 11384808
3. Polymorphisms in glutathione-S-transferase genes (GST-M1, GST-T1 and GST-P1) and susceptibility to prostate cancer among male smokers of the ATBC cancer prevention study.  |  Kidd, LC., et al. 2003. Eur J Cancer Prev. 12: 317-20. PMID: 12883385
4. Polymorphism of glutathione S-transferase (GST) variants and its effect on distribution of urinary arsenic species in people exposed to low inorganic arsenic in tap water: an exploratory study.  |  Caceres, DD., et al. 2010. Arch Environ Occup Health. 65: 140-7. PMID: 20705574
5. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and organic pollutants.  |  Zhang, Y. and Liu, J. 2011. J Hazard Mater. 189: 357-62. PMID: 21411224
6. Association of paraoxonase (PON)1 activity, glutathione S-transferase GST T1/M1 and STin.2 polymorphisms with comorbidity of tobacco use disorder and mood disorders.  |  Vargas Nunes, SO., et al. 2015. Neurosci Lett. 585: 132-7. PMID: 25445355
7. Human placental form of glutathione S-transferase (GST-pi) as a new immunohistochemical marker for human colonic carcinoma.  |  Kodate, C., et al. 1986. Jpn J Cancer Res. 77: 226-9. PMID: 3084412
8. A new mechanism of cancer initiation that involves the transformation of hepatocytes into preneoplastic single hepatocytes and minifoci positive for glutathione S-transferase P-form (GST-P) in rat livers: 3D analysis using a vibratome.  |  Satoh, K. 2024. Cancer Med. 13: e70165. PMID: 39318029
9. A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues.  |  Singhal, SS., et al. 1994. Biochim Biophys Acta. 1204: 279-86. PMID: 8142470
10. Placental glutathione S-transferase (GST-P) induction as a potential mechanism for the anti-carcinogenic effect of the coffee-specific components cafestol and kahweol.  |  Schilter, B., et al. 1996. Carcinogenesis. 17: 2377-84. PMID: 8968051

The preferred GST antibody is GST Antibody (B-14): sc-138.