GS28 Antibody (F-11): sc-271551
- GS28 Antibody (F-11) is a mouse monoclonal IgG2a κ GS28 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-33 at the N-terminus of GS28 of human origin
- GS28 Antibody (F-11) is recommended for detection of GS28 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-GS28 Antibody (F-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for GS28 Antibody (F-11) for WB and IHC(P) applications. These reagents are now offered in bundles with GS28 Antibody (F-11) (see ordering information below).
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GS28 Antibody (F-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects GS28 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). GS28 (F-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GS28 plays a crucial role in the vesicular transport system within eukaryotic cells, specifically in the trafficking of proteins between the endoplasmic reticulum and the Golgi apparatus. This process ensures proteins are correctly modified and delivered to functional destinations, essential for maintaining cellular homeostasis and function. GS28 interaction with other SNARE proteins, such as GS27, facilitates SNARE complex formation, a key component in vesicle fusion with target membranes. This complex brings vesicle and target membranes into close proximity and provides energy necessary for membrane fusion, ensuring efficient transport and protein processing. The human GS28 gene is located on chromosome 17q11, and proper function is critical for cellular communication and protein sorting, making GS28 an important target for research in cellular biology and related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GS28 Antibody (F-11) References:
- cDNA characterization and chromosomal mapping of human golgi SNARE GS27 and GS28 to chromosome 17. | Bui, TD., et al. 1999. Genomics. 57: 285-8. PMID: 10198168
- Deployment of membrane fusion protein domains during fusion. | Bentz, J. and Mittal, A. 2000. Cell Biol Int. 24: 819-38. PMID: 11067767
- Sequential involvement of p115, SNAREs, and Rab proteins in intra-Golgi protein transport. | Gmachl, MJ. and Wimmer, C. 2001. J Biol Chem. 276: 18178-84. PMID: 11279210
- A v-SNARE implicated in intra-Golgi transport. | Nagahama, M., et al. 1996. J Cell Biol. 133: 507-16. PMID: 8636227
- Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. | Hay, JC., et al. 1997. Cell. 89: 149-58. PMID: 9094723
- A SNARE involved in protein transport through the Golgi apparatus. | Lowe, SL., et al. 1997. Nature. 389: 881-4. PMID: 9349823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GS28 Antibody (F-11) | sc-271551 | 200 µg/ml | $316.00 | |||
GS28 Antibody (F-11): m-IgG Fc BP-HRP Bundle | sc-525813 | 200 µg Ab; 10 µg BP | $354.00 | |||
GS28 Antibody (F-11): m-IgG2a BP-HRP Bundle | sc-546424 | 200 µg Ab; 10 µg BP | $354.00 | |||
GS28 Antibody (F-11) AC | sc-271551 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GS28 Antibody (F-11) HRP | sc-271551 HRP | 200 µg/ml | $316.00 | |||
GS28 Antibody (F-11) FITC | sc-271551 FITC | 200 µg/ml | $330.00 | |||
GS28 Antibody (F-11) PE | sc-271551 PE | 200 µg/ml | $343.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 488 | sc-271551 AF488 | 200 µg/ml | $357.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 546 | sc-271551 AF546 | 200 µg/ml | $357.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 594 | sc-271551 AF594 | 200 µg/ml | $357.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 647 | sc-271551 AF647 | 200 µg/ml | $357.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 680 | sc-271551 AF680 | 200 µg/ml | $357.00 | |||
GS28 Antibody (F-11) Alexa Fluor® 790 | sc-271551 AF790 | 200 µg/ml | $357.00 | |||
GS28 (F-11) Neutralizing Peptide | sc-271551 P | 100 µg/0.5 ml | $68.00 |