GRTP1 Antibody (G-6): sc-398974
- GRTP1 Antibody (G-6) is a mouse monoclonal IgG2a κ GRTP1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 99-123 within an internal region of GRTP1 of human origin
- GRTP1 Antibody (G-6) is recommended for detection of GRTP1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-GRTP1 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GRTP1 Antibody (G-6) for WB applications. These reagents are now offered in bundles with GRTP1 Antibody (G-6) (see ordering information below).
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GRTP1 Antibody (G-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects GRTP1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GRTP1 (G-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GRTP1 protein, also known as Growth hormone-regulated TBC protein 1, plays a significant role in cellular processes, particularly in cell cycle regulation and mitosis coordination due to GTPase-activating protein function. GRTP1 is primarily expressed in testis, where levels increase notably after puberty, indicating potential involvement in germ cell development and function. GRTP1′s TBC1 domain is highly conserved and essential for activity, as GRTP1 interacts with small GTPases to modulate signaling pathways critical for cell growth and differentiation. Additionally, GRTP1 has two isoforms resulting from alternative splicing, which may contribute to functional diversity in various tissues. Anti-GRTP1 antibody (G-6)′s ability to effectively detect GRTP1 across multiple species makes this product a valuable tool for researchers studying growth hormone signaling and implications in developmental biology and related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GRTP1 Antibody (G-6) References:
- Grtp1, a novel gene regulated by growth hormone. | Lu, C., et al. 2001. Endocrinology. 142: 4568-71. PMID: 11564724
- TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. | Pan, X., et al. 2006. Nature. 442: 303-6. PMID: 16855591
- Computational analyses of TBC protein family in eukaryotes. | Gao, X., et al. 2008. Protein Pept Lett. 15: 505-9. PMID: 18537741
- Cellular localization of the growth hormone receptor/binding protein in the male and female reproductive systems. | Lobie, PE., et al. 1990. Endocrinology. 126: 2214-21. PMID: 2156686
- Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor does not disturb the course of sexual maturation and fertility in the female rat. | Gruaz, NM., et al. 1994. Endocrinology. 135: 509-19. PMID: 7518382
- Proteins regulating Ras and its relatives. | Boguski, MS. and McCormick, F. 1993. Nature. 366: 643-54. PMID: 8259209
- Growth hormone (GH) therapy markedly increases the motility of spermatozoa and the concentration of insulin-like growth factor-I in seminal vesicle fluid in the male GH-deficient dwarf rat. | Breier, BH., et al. 1996. Endocrinology. 137: 4061-4. PMID: 8756586
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GRTP1 Antibody (G-6) | sc-398974 | 200 µg/ml | $316.00 | |||
GRTP1 Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-530995 | 200 µg Ab; 10 µg BP | $354.00 | |||
GRTP1 Antibody (G-6): m-IgGκ BP-HRP Bundle | sc-524563 | 200 µg Ab, 40 µg BP | $354.00 | |||
GRTP1 Antibody (G-6): m-IgG2a BP-HRP Bundle | sc-547658 | 200 µg Ab; 10 µg BP | $354.00 | |||
GRTP1 Antibody (G-6) AC | sc-398974 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GRTP1 Antibody (G-6) HRP | sc-398974 HRP | 200 µg/ml | $316.00 | |||
GRTP1 Antibody (G-6) FITC | sc-398974 FITC | 200 µg/ml | $330.00 | |||
GRTP1 Antibody (G-6) PE | sc-398974 PE | 200 µg/ml | $343.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 488 | sc-398974 AF488 | 200 µg/ml | $357.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 546 | sc-398974 AF546 | 200 µg/ml | $357.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 594 | sc-398974 AF594 | 200 µg/ml | $357.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 647 | sc-398974 AF647 | 200 µg/ml | $357.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 680 | sc-398974 AF680 | 200 µg/ml | $357.00 | |||
GRTP1 Antibody (G-6) Alexa Fluor® 790 | sc-398974 AF790 | 200 µg/ml | $357.00 | |||
GRTP1 (G-6) Neutralizing Peptide | sc-398974 P | 100 µg/0.5 ml | $68.00 |