GRK 2 Antibody (E-7): sc-166283
- GRK 2 Antibody (E-7) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 661-689 at the C-terminus of GRK 2 of human origin
- recommended for detection of GRK 2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and porcine
- See GRK 2 (C-9): sc-13143 for GRK 2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GRK 2 Antibody (E-7). This work is in progress.
GRK 2 Antibody (E-7) is a mouse monoclonal IgG2b antibody that detects GRK 2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GRK 2, a member of the G protein-coupled receptor kinase family, plays a crucial role in the regulation of G protein-coupled receptor signaling by phosphorylating activated receptors, which leads to their desensitization and internalization. This process is vital for maintaining cellular responsiveness to external signals, as it prevents overstimulation and allows for the fine-tuning of physiological responses. The ability of GRK 2 (E-7) antibody to specifically phosphorylate receptors in their active state underscores its importance in modulating signal transduction pathways, which can have significant implications in various physiological processes and disease states. Anti-GRK 2 antibody (E-7) is an essential tool for researchers studying receptor signaling dynamics and the intricate mechanisms of cellular communication.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GRK 2 Antibody (E-7) | sc-166283 | 200 µg/ml | $322.00 | |||
GRK 2 (E-7) Neutralizing Peptide | sc-166283 P | 100 µg/0.5 ml | $69.00 |