Gram Negative Endotoxin Marker Antibody (1.B.293): sc-71172
- Gram Negative Endotoxin Marker Antibody (1.B.293) is a mouse monoclonal IgG2b provided at 100 µl ascites
- raised against O:111 B4 J5 cells of E. coli origin
- recommended for detection of Gram Negative Endotoxin of E. coli origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Gram Negative Endotoxin Marker Antibody (1.B.293). This work is in progress.
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Gram Negative Endotoxin Marker Antibody (1.B.293) is a mouse monoclonal IgG2b antibody that detects Gram Negative Endotoxin of E. coli origin by enzyme-linked immunosorbent assay (ELISA). Anti-Gram Negative Endotoxin Marker antibody (1.B.293) is available as a non-conjugated monoclonal isotype antibody. Gram Negative Endotoxin, primarily composed of lipopolysaccharide (LPS), plays a crucial role in the structural integrity of Gram-negative bacteria, which are characterized by their unique cell wall composition. Unlike Gram-positive bacteria, which have a thick peptidoglycan layer, Gram-negative bacteria possess a thin peptidoglycan layer surrounded by an outer membrane rich in LPS. This structural arrangement not only protects the bacteria from environmental threats but also contributes to their pathogenicity, as LPS can trigger intense immune responses in host organisms. The presence of LPS in the bacterial cell wall is significant because LPS serves as a major virulence factor, enabling Gram-negative bacteria to evade the host′s immune system and establish infections. Understanding the role of Gram Negative Endotoxin is essential for developing therapeutic strategies and diagnostic tools aimed at combating infections caused by these bacteria.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gram Negative Endotoxin Marker Antibody (1.B.293) | sc-71172 | 100 µl ascites | $322.00 |