GPR56 Antibody (G-6): sc-390192
- GPR56 Antibody (G-6) is a mouse monoclonal IgG1 κ GPR56 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 289-381 mapping within an internal region of GPR56 of human origin
- GPR56 Antibody (G-6) is recommended for detection of GPR56 of human origin by WB, IP, IF and ELISA
- Anti-GPR56 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GPR56 Antibody (G-6) for WB applications. These reagents are now offered in bundles with GPR56 Antibody (G-6) (see ordering information below).
GPR56 Antibody (G-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects GPR56 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GPR56 monoclonal antibody (G-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GPR56, also known as TM7XN1 protein, is a member of the G protein-coupled receptor (GPCR) family, which is the largest protein family in the human genome and plays a crucial role in mediating a wide range of physiological processes by converting extracellular signals into intracellular responses. This receptor is integral to cell-cell interactions and is predominantly expressed in the brain, heart, and thyroid gland, highlighting its importance in neural and cardiovascular functions. Notably, GPR56 contains a GPS domain and is involved in the regulation of cortical development; mutations in the GPR56 gene can lead to bilateral frontoparietal polymicrogyria (BFPP), a condition characterized by abnormal cortical layering that can result in severe neurological deficits. The ability of GPR56 to interact with various signaling molecules, including hormones and neurotransmitters, underscores its significance in maintaining cellular communication and homeostasis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GPR56 Antibody (G-6) References:
- GPR56, a novel secretin-like human G-protein-coupled receptor gene. | Liu, M., et al. 1999. Genomics. 55: 296-305. PMID: 10049584
- TM7XN1, a novel human EGF-TM7-like cDNA, detected with mRNA differential display using human melanoma cell lines with different metastatic potential. | Zendman, AJ., et al. 1999. FEBS Lett. 446: 292-8. PMID: 10100861
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. | Clark, HF., et al. 2003. Genome Res. 13: 2265-70. PMID: 12975309
- G protein-coupled receptor-dependent development of human frontal cortex. | Piao, X., et al. 2004. Science. 303: 2033-6. PMID: 15044805
- GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion. | Shashidhar, S., et al. 2005. Oncogene. 24: 1673-82. PMID: 15674329
- Genetics of the polymicrogyria syndromes. | Jansen, A. and Andermann, E. 2005. J Med Genet. 42: 369-78. PMID: 15863665
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GPR56 Antibody (G-6) | sc-390192 | 200 µg/ml | $322.00 | |||
GPR56 Antibody (G-6): m-IgGκ BP-HRP Bundle | sc-523441 | 200 µg Ab, 40 µg BP | $361.00 | |||
GPR56 Antibody (G-6): m-IgG1 BP-HRP Bundle | sc-533583 | 200 µg Ab; 20 µg BP | $361.00 | |||
GPR56 Antibody (G-6) AC | sc-390192 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GPR56 Antibody (G-6) HRP | sc-390192 HRP | 200 µg/ml | $322.00 | |||
GPR56 Antibody (G-6) FITC | sc-390192 FITC | 200 µg/ml | $336.00 | |||
GPR56 Antibody (G-6) PE | sc-390192 PE | 200 µg/ml | $349.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 488 | sc-390192 AF488 | 200 µg/ml | $364.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 546 | sc-390192 AF546 | 200 µg/ml | $364.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 594 | sc-390192 AF594 | 200 µg/ml | $364.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 647 | sc-390192 AF647 | 200 µg/ml | $364.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 680 | sc-390192 AF680 | 200 µg/ml | $364.00 | |||
GPR56 Antibody (G-6) Alexa Fluor® 790 | sc-390192 AF790 | 200 µg/ml | $364.00 |