GPR175 Antibody (6H2): sc-134350

GPR175 Antibody (6H2) is a mouse monoclonal IgG2b kappa light chain antibody that detects GPR175 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). GPR175 (6H2) antibody is available as the non-conjugated form. GPR175, also known as TPRA40 or PP6566, is a 373 amino acid multi-pass membrane protein that plays a crucial role in various physiological processes as a member of the G protein-coupled receptor superfamily. These receptors are integral to the transmission of extracellular signals into the cell, facilitating responses to hormones and neurotransmitters. GPR175 modulates intracellular signaling pathways, which can influence numerous biological functions, including mood regulation and metabolic processes. The gene encoding GPR175 is located on human chromosome 3 and expresses multiple alternatively spliced isoforms, highlighting potential diverse functional roles in different tissues. Widespread expression of GPR175 across various cell types underscores significance in maintaining cellular communication and response mechanisms, making anti-GPR175 antibody (6H2) an essential tool for researchers studying intricate signaling networks in health and disease.

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GPR175 Antibody (6H2) References:

1. Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice.  |  Yang, H., et al. 1999. Endocrinology. 140: 2859-67. PMID: 10342878
2. TPRA40/GPR175 regulates early mouse embryogenesis through functional membrane transport by Sjögren's syndrome-associated protein NA14.  |  Aki, T., et al. 2008. J Cell Physiol. 217: 194-206. PMID: 18459117
3. The receptor revolution--multiplicity of G-protein-coupled receptors.  |  Larhammar, D., et al. 1993. Drug Des Discov. 9: 179-88. PMID: 8400001
4. G protein-coupled receptors. I. Diversity of receptor-ligand interactions.  |  Ji, TH., et al. 1998. J Biol Chem. 273: 17299-302. PMID: 9651309

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GPR175 Antibody (6H2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-GPR175 Antibody (6H2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GPR175 Antibody (6H2) Specifications

Alternate Product Name: GPR175

Product Clone Name: 6H2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 281-372

Epitope Target: GPR175

Epitope Species: human

Product Reactivity/Detection: GPR175

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for GPR175 Antibody (6H2): N/A