GPNMB Antibody (G-8): sc-271416
- GPNMB Antibody (G-8) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 38-158 mapping near the N-terminus of GPNMB of human origin
- recommended for detection of GPNMB isoforms 1 and 2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for GPNMB Antibody (G-8) for WB applications. These reagents are now offered in bundles with GPNMB Antibody (G-8) (see ordering information below).
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SEE ALSO...
GPNMB Antibody (G-8) is a mouse monoclonal IgG2a antibody that detects GPNMB in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GPNMB, also known as hematopoietic growth factor inducible neurokinin-1 (HGFIN), is a single-pass type I transmembrane glycoprotein that plays a crucial role in various biological processes, including melanogenesis and lymphohematopoietic stem cell maturation. GPNMB is primarily expressed in poorly metastatic melanoma cell lines, highlighting potential significance in cancer biology, particularly in understanding tumor progression and metastasis. GPNMB expression is absent in highly metastatic melanoma cell lines, suggesting a role as a marker for less aggressive tumor phenotypes. GPNMB′s structure, characterized by a single-pass membrane domain, facilitates interactions with other cellular components and signaling pathways essential for maintaining cellular homeostasis and regulating processes such as cell proliferation and differentiation. anti-GPNMB antibody (G-8) serves as an invaluable tool for researchers exploring GPNMB′s multifaceted roles in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GPNMB Antibody (G-8) | sc-271416 | 200 µg/ml | $322.00 | |||
GPNMB Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-540238 | 200 µg Ab; 10 µg BP | $361.00 | |||
GPNMB Antibody (G-8): m-IgG2a BP-HRP Bundle | sc-546874 | 200 µg Ab; 10 µg BP | $361.00 |