GLIPR1L2 Antibody (B-12): sc-514645
- GLIPR1L2 Antibody (B-12) is a mouse monoclonal IgG1 κ GLIPR1L2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 46-70 near the N-terminus of GLIPR1L2 of human origin
- GLIPR1L2 Antibody (B-12) is recommended for detection of GLIPR1L2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-GLIPR1L2 Antibody (B-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for GLIPR1L2 Antibody (B-12) for WB and IHC(P) applications. These reagents are now offered in bundles with GLIPR1L2 Antibody (B-12) (see ordering information below).
QUICK LINKS
GLIPR1L2 Antibody (B-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects GLIPR1L2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GLIPR1L2 (B-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GLIPR1L2, a member of the glioma pathogenesis-related 1 family, plays a crucial role in cellular processes such as immunity and cell adhesion, which are vital for maintaining tissue integrity and responding to pathological conditions. This 344 amino acid single-pass membrane protein is predominantly expressed in the testis, with additional expression in the prostate, kidney, bladder, lung, and bone marrow, highlighting its potential significance in reproductive health and other physiological functions. Notably, GLIPR1L2 exists as six isoforms due to alternative splicing, which may contribute to its functional diversity and regulatory mechanisms in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GLIPR1L2 Antibody (B-12) References:
- Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster. | Ren, C., et al. 2006. Genomics. 88: 163-72. PMID: 16714093
- Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. | Chilukamarri, L., et al. 2007. Neoplasia. 9: 970-8. PMID: 18030365
- Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. | Li, L., et al. 2008. Cancer Res. 68: 434-43. PMID: 18199537
- The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins--roles in reproduction, cancer, and immune defense. | Gibbs, GM., et al. 2008. Endocr Rev. 29: 865-97. PMID: 18824526
- Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding. | Gibbs, GM., et al. 2010. Endocrinology. 151: 2331-42. PMID: 20219979
- Glioma pathogenesis-related protein 1: tumor-suppressor activities and therapeutic potential. | Thompson, TC. 2010. Yonsei Med J. 51: 479-83. PMID: 20499410
- Examining Hedgehog pathway genes GLI3, SHH, and PTCH1 and the p53 target GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster using fluorescence in situ hybridization uncovers GLIPR1/GLIPR1L1/GLIPR1L2 deletion in 9% of patients with multiple myeloma. | Tam, M., et al. 2010. J Assoc Genet Technol. 36: 111-4. PMID: 20978342
- Cloning and expression of a novel component of the CAP superfamily enhanced in the inflammatory response to LPS of the ascidian Ciona intestinalis. | Bonura, A., et al. 2010. Cell Tissue Res. 342: 411-21. PMID: 21086138
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GLIPR1L2 Antibody (B-12) | sc-514645 | 200 µg/ml | $322.00 | |||
GLIPR1L2 Antibody (B-12): m-IgG Fc BP-HRP Bundle | sc-527926 | 200 µg Ab; 10 µg BP | $361.00 | |||
GLIPR1L2 Antibody (B-12): m-IgG1 BP-HRP Bundle | sc-533299 | 200 µg Ab; 20 µg BP | $361.00 | |||
GLIPR1L2 Antibody (B-12) AC | sc-514645 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GLIPR1L2 Antibody (B-12) HRP | sc-514645 HRP | 200 µg/ml | $322.00 | |||
GLIPR1L2 Antibody (B-12) FITC | sc-514645 FITC | 200 µg/ml | $336.00 | |||
GLIPR1L2 Antibody (B-12) PE | sc-514645 PE | 200 µg/ml | $349.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 488 | sc-514645 AF488 | 200 µg/ml | $364.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 546 | sc-514645 AF546 | 200 µg/ml | $364.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 594 | sc-514645 AF594 | 200 µg/ml | $364.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 647 | sc-514645 AF647 | 200 µg/ml | $364.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 680 | sc-514645 AF680 | 200 µg/ml | $364.00 | |||
GLIPR1L2 Antibody (B-12) Alexa Fluor® 790 | sc-514645 AF790 | 200 µg/ml | $364.00 | |||
GLIPR1L2 (B-12) Neutralizing Peptide | sc-514645 P | 100 µg/0.5 ml | $69.00 |