GlcAT-I Antibody (H-5): sc-390526
- GlcAT-I Antibody (H-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 319-334 of GlcAT-I of human origin
- recommended for detection of GlcAT-I of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for GlcAT-I Antibody (H-5) for WB applications. These reagents are now offered in bundles with GlcAT-I Antibody (H-5) (see ordering information below).
QUICK LINKS
GlcAT-I Antibody (H-5) is a mouse monoclonal IgG1 antibody that detects GlcAT-I in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GlcAT-I, also known as beta-1,3-glucuronyltransferase 3 (B3GAT3), is a crucial 335 amino acid single-pass type II membrane protein that plays a significant role in proteoglycan biosynthesis by catalyzing glycosaminoglycan-protein linkage formation. GlcAT-I (H-5) antibody targets a protein essential for proper extracellular matrix assembly, which maintains tissue structure and function. GlcAT-I operates using manganese as a cofactor and exhibits strict specificity for the substrate Gal-beta-1,3-Gal-beta-1,4-Xyl, forming a disulfide-linked homodimer predominantly localized to the Golgi apparatus membrane. Additionally, GlcAT-I undergoes N-glycosylation, which is important for stability and function, influencing interactions with other proteins and cellular components. Anti-GlcAT-I antibody (H-5) serves as an invaluable tool for researchers studying proteoglycan biosynthesis dynamics and implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GlcAT-I Antibody (H-5) | sc-390526 | 200 µg/ml | $316.00 | |||
GlcAT-I Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-540809 | 200 µg Ab; 10 µg BP | $354.00 | |||
GlcAT-I Antibody (H-5): m-IgG1 BP-HRP Bundle | sc-542383 | 200 µg Ab; 20 µg BP | $354.00 | |||
GlcAT-I (H-5) Neutralizing Peptide | sc-390526 P | 100 µg/0.5 ml | $68.00 |