GH Antibody (C-3): sc-166696

GH Antibody (C-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects Growth Hormone (GH) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GH Antibody (C-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Growth Hormone, also known as somatotropin, is synthesized by the acidophilic or somatotropic cells of the anterior pituitary gland, consisting of 191 amino acid residues linked by two disulfide bridges. Growth Hormone plays a vital role in regulating growth, metabolism, and differentiation across various mammalian cell types by modulating the synthesis of multiple mRNA species. Growth Hormone exerts effects through binding to GHR, initiating a phosphorylation cascade that influences numerous signaling pathways essential for cellular function. Growth Hormone secretion follows a pulsatile pattern, controlled by hypothalamic factors GH-releasing hormone (GHRH) and somatostatin (SRIF), which together regulate Growth Hormone synthesis and secretory reserve. Growth Hormone output is subject to feedback regulation by Growth Hormone levels and insulin-like growth factor I, highlighting complex regulatory mechanisms. Growth Hormone interaction with various signaling pathways underscores importance in growth and metabolic processes, making anti-GH antibody (C-3) an invaluable tool for researchers studying these critical biological functions.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GH Antibody (C-3) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-GH Antibody (C-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GH Antibody (C-3) Specifications

Alternate Product Name: Growth Hormone

Product Clone Name: C-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 45-64

Epitope Target: GH

Epitope Species: human

Product Reactivity/Detection: GH-1, GH-2 and Lactogen (chorionic somatommamotropin) of human origin, and GH of mouse and rat origin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for GH Antibody (C-3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred GH antibody is GH Antibody (E-7): sc-374266.