Gemin2 Antibody (E-7): sc-166162
- Gemin2 Antibody (E-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 2-101 mapping at the N-terminus of Gemin2 of human origin
- recommended for detection of Gemin2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Gemin2 Antibody (E-7) for WB and IHC(P) applications. These reagents are now offered in bundles with Gemin2 Antibody (E-7) (see ordering information below).
Gemin2 Antibody (E-7) is a mouse monoclonal IgG1 antibody that detects Gemin2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Gemin2 plays a crucial role in the assembly of the survival of motor neuron (SMN) complex, which is essential for the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) that are vital for pre-mRNA splicing. This process is critical for gene expression regulation and the proper functioning of cellular processes, as splicing errors can lead to various diseases, including spinal muscular atrophy. Gemin2 is predominantly located in both the cytoplasm and the nucleus, where Gemin2 is concentrated in subnuclear structures known as gems, which are involved in the storage and assembly of snRNPs. The presence of Gemin2 in these cellular compartments underscores Gemin2′s importance in maintaining the integrity of the splicing machinery and highlights Gemin2′s potential as a therapeutic target in conditions associated with splicing dysregulation. Anti-Gemin2 antibody (E-7) is particularly valuable for researchers studying the molecular mechanisms underlying neurodegenerative diseases and the role of splicing in cellular health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gemin2 Antibody (E-7) | sc-166162 | 200 µg/ml | $316.00 | |||
Gemin2 Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-540031 | 200 µg Ab; 10 µg BP | $354.00 | |||
Gemin2 Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-541859 | 200 µg Ab; 20 µg BP | $354.00 |