Gastric Lipase Antibody (H-8): sc-390749
- Gastric Lipase Antibody (H-8) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 291-360 mapping near the C-terminus of Gastric Lipase of human origin
- recommended for detection of Gastric Lipase of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG1 BP-HRP is the preferred secondary detection reagent for Gastric Lipase Antibody (H-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with Gastric Lipase Antibody (H-8) (see ordering information below).
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Gastric Lipase Antibody (H-8) is a mouse monoclonal IgG1 antibody that detects Gastric Lipase in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Gastric Lipase is a 379-amino acid protein that plays a vital role in the digestion of dietary triglycerides, particularly in individuals with pancreatic lipase deficiencies, making Gastric Lipase essential for proper nutrient absorption. This enzyme is secreted by the fundic mucosa of the stomach and operates optimally under acidic pH conditions, where Gastric Lipase hydrolyzes the ester bonds of triglycerides, facilitating their breakdown into absorbable fatty acids and glycerol. The importance of Gastric Lipase extends beyond mere digestion; Gastric Lipase activity is crucial for maintaining lipid homeostasis and ensuring that the body can efficiently utilize dietary fats. Additionally, Gastric Lipase interactions with other digestive enzymes and regulation by various factors highlight Gastric Lipase significance in gastrointestinal health and metabolic processes. Gastric Lipase antibody (H-8) is an invaluable tool for researchers studying lipid metabolism and related disorders, providing insights into the physiological and pathological roles of this critical enzyme.
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Gastric Lipase Antibody (H-8) References:
- Gastric lipase and pancreatic exocrine insufficiency. | Layer, P. and Keller, J. 2005. Clin Gastroenterol Hepatol. 3: 25-7. PMID: 15645400
- Immunocytolocalization of human gastric lipase in chief cells of the fundic mucosa. | Moreau, H., et al. 1989. Histochemistry. 91: 419-23. PMID: 2656594
- Lingual and gastric lipases: species differences in the origin of prepancreatic digestive lipases and in the localization of gastric lipase. | DeNigris, SJ., et al. 1988. Biochim Biophys Acta. 959: 38-45. PMID: 3125856
- Arabidopsis Hairy Roots Producing High Level of Active Human Gastric Lipase. | Guerineau, F., et al. 2020. Mol Biotechnol. 62: 168-176. PMID: 31893339
- Human gastric lipase: variations induced by gastrointestinal hormones and by pathology. | Moreau, H., et al. 1988. Scand J Gastroenterol. 23: 1044-8. PMID: 3247586
- Effects of recombinant human gastric lipase and pancreatin during in vitro pediatric gastro-intestinal digestion. | Heerup, C., et al. 2021. Food Funct. 12: 2938-2949. PMID: 33710204
- Gastric lipase can significantly increase lipolysis and carotenoid bioaccessibility from plant food matrices in the harmonized INFOGEST static in vitro digestion model. | Iddir, M., et al. 2021. Food Funct. 12: 9043-9053. PMID: 34608921
- Secretion of human gastric lipase from dispersed gastric glands. | DeNigris, SJ., et al. 1985. Biochim Biophys Acta. 836: 67-72. PMID: 4027260
- Ontogeny of human gastric lipase and pepsin activities. | Ménard, D., et al. 1995. Gastroenterology. 108: 1650-6. PMID: 7768368
- Secretin and gastric lipase secretion. | Olsen, O., et al. 1998. Digestion. 59: 655-9. PMID: 9813389
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gastric Lipase Antibody (H-8) | sc-390749 | 200 µg/ml | $322.00 | |||
Gastric Lipase Antibody (H-8): m-IgG1 BP-HRP Bundle | sc-542710 | 200 µg Ab; 20 µg BP | $361.00 |