Gastric Lipase Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
THL acts as a selective inhibitor of gastric lipase, engaging in specific interactions with the enzyme's active site. Its unique structure allows for the formation of stable enzyme-inhibitor complexes, effectively blocking substrate access. The compound exhibits distinct reaction kinetics, characterized by a non-competitive inhibition mechanism that alters lipid digestion pathways. This modulation of enzymatic activity can significantly impact lipid metabolism and energy homeostasis. | ||||||
Citilistat | 282526-98-1 | sc-358100 sc-358100A | 250 mg 1 g | $46.00 $102.00 | ||
Cetilistat is another pancreatic lipase inhibitor similar to Orlistat. It functions by binding to gastric lipase, inhibiting its activity and reducing the hydrolysis of dietary fats. The blocked lipase activity results in reduced fat absorption, contributing to its role in weight management. | ||||||
Polysorbate 80 | 9005-65-6 | sc-255444 sc-255444A sc-255444B sc-255444C | 100 ml 500 ml 1 L 5 L | $23.00 $41.00 $51.00 $153.00 | 4 | |
Polysorbate 80 is a non-ionic surfactant that indirectly modulates gastric lipase activity. By affecting the micellar solubilization of lipids, Polysorbate 80 can influence the availability of lipids for enzymatic hydrolysis. Its actions on the solubilization process can indirectly impact gastric lipase activity, suggesting a potential role in controlling lipid digestion and absorption. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
Simvastatin is an HMG-CoA reductase inhibitor that indirectly influences gastric lipase activity. By reducing cholesterol synthesis through inhibition of HMG-CoA reductase, Simvastatin alters the composition of lipoproteins and their interactions with gastric lipase. This indirect modulation may impact the availability of lipids for enzymatic hydrolysis, suggesting a potential link between cholesterol metabolism and gastric lipase activity. | ||||||
Sorbitan monostearate | 1338-41-6 | sc-281152 sc-281152A sc-281152B sc-281152C | 250 g 1 kg 5 kg 10 kg | $42.00 $88.00 $300.00 $500.00 | ||
Sorbitan monostearate is a surfactant that indirectly influences gastric lipase activity. By altering the emulsification properties of lipids, Sorbitan monostearate can impact the accessibility of lipids for gastric lipase hydrolysis. This indirect modulation may affect the efficiency of lipid digestion and absorption in the gastrointestinal tract. | ||||||
Acarbose | 56180-94-0 | sc-203492 sc-203492A | 1 g 5 g | $222.00 $593.00 | 1 | |
Acarbose is an alpha-glucosidase inhibitor that indirectly modulates gastric lipase activity. By inhibiting alpha-glucosidase enzymes, Acarbose interferes with the breakdown of complex carbohydrates into absorbable sugars. This modulation may alter the composition of lipids available for gastric lipase hydrolysis, suggesting a connection between carbohydrate metabolism and gastric lipase activity. | ||||||
Nonaethylene glycol monododecyl ether | 3055-99-0 | sc-281106 sc-281106A | 50 g 100 g | $180.00 $315.00 | ||
Nonaethylene glycol monododecyl ether (Polidocanol) is a sclerosing agent that indirectly influences gastric lipase activity. Through its actions on lipid-containing micelles, Polidocanol can impact the availability of lipids for enzymatic hydrolysis by gastric lipase. This indirect modulation may contribute to the alteration of lipid digestion and absorption in the gastrointestinal tract. | ||||||
Nafamostat mesylate | 82956-11-4 | sc-201307 sc-201307A | 10 mg 50 mg | $80.00 $300.00 | 4 | |
Nafamostat mesylate is a serine protease inhibitor that indirectly influences gastric lipase activity. By inhibiting serine proteases, Nafamostat mesylate may impact the enzymatic processes involved in lipid digestion and absorption. This indirect modulation suggests a potential link between protease activity and gastric lipase function, providing insights into the regulatory mechanisms of lipid metabolism. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $70.00 $290.00 $600.00 | 19 | |
Caffeic acid phenethyl ester is a bioactive compound that indirectly modulates gastric lipase activity. Through its anti-inflammatory and antioxidant properties, it may influence cellular processes associated with lipid metabolism. This indirect modulation suggests a potential link between inflammatory responses and gastric lipase activity, providing insights into the complex regulation of lipid digestion and absorption. | ||||||