γ Enolase Antibody (3F290): sc-71046
- γ Enolase Antibody (3F290) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 416-433 of γ Enolase of human origin
- recommended for detection of γ Enolase of mouse, rat and human origin by WB, IP and IF
- See Enolase (A-5): sc-271384 for γ Enolase antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for γ Enolase Antibody (3F290) for WB applications. These reagents are now offered in bundles with γ Enolase Antibody (3F290) (see ordering information below).
γ Enolase Antibody (3F290) is a mouse monoclonal IgG1 antibody that detects γ Enolase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). γ Enolase, one of the three isoenzymes of enolase, is primarily expressed in nervous tissue and plays a crucial role in the glycolytic pathway by catalyzing the conversion of 2-phosphoglycerate to phosphoenolpyruvate, a key step in energy production. This enzymatic function is particularly important in neurons, where energy demands are high, and disruptions in glycolytic processes can lead to neurodegenerative diseases. The γ Enolase isoform is also known to be involved in cellular differentiation and has been implicated in various pathological conditions, making γ Enolase a significant marker for research in neurobiology and cancer. Anti-γ Enolase antibody (3F290) provides reliable detection and quantification of γ Enolase, facilitating studies aimed at understanding its role in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
γ Enolase Antibody (3F290) References:
- Neuron-specific enolase (gamma enolase, gamma-gamma dimer) expression in Hodgkin's disease and large cell lymphomas. | Massarelli, G., et al. 1999. Anticancer Res. 19: 3933-8. PMID: 10628334
- Differential modulation of alpha, beta and gamma enolase isoforms in regenerating mouse skeletal muscle. | Merkulova, T., et al. 2000. Eur J Biochem. 267: 3735-43. PMID: 10848992
- Cloning, expression and sequence homologies of cDNA for human gamma enolase. | Oliva, D., et al. 1989. Gene. 79: 355-60. PMID: 2792767
- Complex of brain D-phosphoglycerate mutase and gamma enolase and its reactivation by D-glycerate 2,3-bisphosphate. | Batke, J., et al. 1988. Arch Biochem Biophys. 264: 510-8. PMID: 2840859
- Quercetin attenuates the injury-induced reduction of γ-enolase expression in a middle cerebral artery occlusion animal model. | Jeon, SJ., et al. 2017. Lab Anim Res. 33: 308-314. PMID: 29399028
- Human gamma enolase: isolation of a cDNA clone and expression in normal and tumor tissues of human origin. | Van Obberghen, E., et al. 1988. J Neurosci Res. 19: 450-6. PMID: 3385803
- Developmental expression of alpha- and gamma-enolase subunits and mRNA sequences in the mouse brain. | Lucas, M., et al. 1988. Dev Neurosci. 10: 91-8. PMID: 3402359
- Purification of gamma-enolase messenger ribonucleic acid from rat brain by an immunoadsorption method. | Nybroe, O., et al. 1985. Neurosci Lett. 53: 115-9. PMID: 3887224
- Coexpression of alpha and gamma enolase genes in neurons of adult rat brain. | Keller, A., et al. 1994. J Neurosci Res. 38: 493-504. PMID: 7815469
- Elevated concentrations of gamma-enolase in renal cell tumors in rats: similarity to renal cell carcinoma in man. | Takashi, M., et al. 1996. Urol Res. 24: 375-9. PMID: 9008332
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
γ Enolase Antibody (3F290) | sc-71046 | 200 µg/ml | $322.00 | |||
γ Enolase Antibody (3F290): m-IgG Fc BP-HRP Bundle | sc-539336 | 200 µg Ab; 10 µg BP | $361.00 | |||
γ Enolase Antibody (3F290): m-IgG1 BP-HRP Bundle | sc-541419 | 200 µg Ab; 20 µg BP | $361.00 |