γ Enolase Antibody (3F289): sc-71047

γ Enolase Antibody (3F289) is a mouse monoclonal IgG1 antibody that detects γ Enolase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). γ Enolase, one of the three isoenzymes of enolase, is primarily expressed in nervous tissue, where anti-γ Enolase antibody (3F289) plays a crucial role in the glycolytic pathway by catalyzing the conversion of 2-phosphoglycerate to phosphoenolpyruvate, a key step in energy production. This enzymatic function is particularly important in neurons, as γ Enolase supports their high metabolic demands and contributes to the maintenance of cellular energy levels, which are vital for proper neuronal function and signaling. The presence of γ Enolase in the nervous system also makes γ Enolase (3F289) antibody a potential biomarker for neurological disorders, as alterations in expression can indicate pathological changes. γ Enolase monoclonal antibody (3F289) provides reliable detection and characterization of this important protein, facilitating research into its role in both normal physiology and disease states.

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γ Enolase Antibody (3F289) References:

1. Measurement of gamma-enolase release, a new method for selective quantification of neurotoxicity independently from glial lysis.  |  Lafon-Cazal, M., et al. 1992. Brain Res. 593: 63-8. PMID: 1458320
2. Hippocampal levels of gamma-enolase, C-1-tetrahydrofolate synthase and serotransferrin fluctuate over the estrous cycle in the rat.  |  Diao, WF., et al. 2008. Neuroscience. 154: 1009-20. PMID: 18511206
3. γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways.  |  Hafner, A., et al. 2012. Biochem J. 443: 439-50. PMID: 22257123
4. Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X.  |  Hafner, A., et al. 2013. Aging Cell. 12: 604-14. PMID: 23621429
5. Evaluation of gamma-enolase as a tumor marker for renal cell carcinoma.  |  Takashi, M., et al. 1989. J Urol. 141: 830-4. PMID: 2648028
6. Curcumin attenuates the middle cerebral artery occlusion-induced reduction in γ-enolase expression in an animal model.  |  Gim, SA., et al. 2015. Lab Anim Res. 31: 198-203. PMID: 26755923
7. Gamma-enolase activity in choroidal melanoma.  |  Margo, CE. and Lavellée, M. 1986. Graefes Arch Clin Exp Ophthalmol. 224: 374-6. PMID: 3710193
8. Immunohistochemical localization of gamma-enolase in normal human tissues other than nervous and neuroendocrine tissues.  |  Haimoto, H., et al. 1985. Lab Invest. 52: 257-63. PMID: 3974199
9. Serum gamma-enolase and prognosis of patients with renal cell carcinoma.  |  Rasmuson, T., et al. 1993. Cancer. 72: 1324-8. PMID: 8339221
10. A comparative study of the distribution of alpha- and gamma-enolase subunits in cultured rat neural cells and fibroblasts.  |  Deloulme, JC., et al. 1997. Int J Dev Neurosci. 15: 183-94. PMID: 9178037

The preferred γ Enolase antibody is γ Enolase Antibody (D-7): sc-376375.