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GalNAc-T14 Antibody (A-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects GalNAc-T14 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). GalNAc-T14 (A-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GalNAc-T14, also known as UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14, plays a crucial role in initiating mucin-type O-linked glycosylation, a process vital for protein stability, cell signaling, and protective mucosal barrier formation. This 552 amino acid single-pass type II membrane protein is primarily localized in the Golgi apparatus, where GalNAc-T14 utilizes calcium and manganese as cofactors to transfer N-acetylgalactosamine to serine and threonine residues on target proteins. A Ricin B-type lectin domain in GalNAc-T14′s structure suggests specific interaction with carbohydrate moieties, essential for substrate specificity. GalNAc-T14 is highly expressed in fetal and adult kidney tissues and exists in multiple alternatively spliced isoforms, highlighting GalNAc-T14′s importance in developmental processes and potential implications in kidney function and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GalNAc-T14 Antibody (A-8) | sc-393051 | 200 µg/ml | $316.00 | |||
GalNAc-T14 Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-530340 | 200 µg Ab; 10 µg BP | $354.00 | |||
GalNAc-T14 Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-523785 | 200 µg Ab, 40 µg BP | $354.00 | |||
GalNAc-T14 Antibody (A-8) AC | sc-393051 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GalNAc-T14 Antibody (A-8) HRP | sc-393051 HRP | 200 µg/ml | $316.00 | |||
GalNAc-T14 Antibody (A-8) FITC | sc-393051 FITC | 200 µg/ml | $330.00 | |||
GalNAc-T14 Antibody (A-8) PE | sc-393051 PE | 200 µg/ml | $343.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 488 | sc-393051 AF488 | 200 µg/ml | $357.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 546 | sc-393051 AF546 | 200 µg/ml | $357.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 594 | sc-393051 AF594 | 200 µg/ml | $357.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 647 | sc-393051 AF647 | 200 µg/ml | $357.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 680 | sc-393051 AF680 | 200 µg/ml | $357.00 | |||
GalNAc-T14 Antibody (A-8) Alexa Fluor® 790 | sc-393051 AF790 | 200 µg/ml | $357.00 |