GABP-β1/2 Antibody (E-7) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
raised against amino acids 131-395 mapping at the C-terminus of GABP-β1 of human origin
GABP- beta 1/2 Antibody (E-7) is recommended for detection of GABP-β1 and GABP-β2 of human origin by WB, IP, IF and ELISA
Anti-GABP- beta 1/2 Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-271571 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of GABP-β1/2 (E-7): sc-271571.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for GABP-β1/2 Antibody (E-7) for WB applications. These reagents are now offered in bundles with GABP-β1/2 Antibody (E-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-α and a GABP-α-associated subunit, GABPβ. GABPα binds to a specific DNA sequence and GABPβ exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABPβ is expressed in both the cytoplasm and the nucleus, whereas GABPα is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABPαβ heterodimer or a GABPαb heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABPαβ tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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