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FUS/TLS Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects FUS/TLS in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). FUS/TLS, a nuclear RNA-binding protein, plays a crucial role in the regulation of gene expression and RNA processing, which is vital for maintaining cellular homeostasis and responding to stress signals. FUS/TLS antibody (D-8) recognizes a protein that interacts with nuclear steroid receptors, suggesting involvement in hormone-induced transcriptional regulation and various physiological processes. Additionally, FUS/TLS forms complexes with TFIID, indicating potential roles in transcriptional machinery and primary transcript processing. Chromosomal translocations causing aberrant fusion of FUS/TLS with other proteins can lead to oncogenic transformations, highlighting FUS/TLS′s significance in cancer research. Anti-FUS/TLS antibody (D-8) serves as a reliable tool for exploring functional dynamics in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FUS/TLS Antibody (D-8) | sc-373888 | 200 µg/ml | $316.00 | |||
FUS/TLS Antibody (D-8): m-IgG Fc BP-HRP Bundle | sc-537882 | 200 µg Ab; 10 µg BP | $354.00 | |||
FUS/TLS Antibody (D-8): m-IgGκ BP-HRP Bundle | sc-535330 | 200 µg Ab; 40 µg BP | $354.00 | |||
FUS/TLS Antibody (D-8): m-IgG1 BP-HRP Bundle | sc-545426 | 200 µg Ab; 20 µg BP | $354.00 |