Date published: 2025-12-11

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FUS/TLS Antibody (D-8): sc-373888

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Datasheets
  • FUS/TLS Antibody (D-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
  • raised against amino acids 451-526 of FUS/TLS of human origin
  • recommended for detection of FUS/TLS of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See FUS/TLS (4H11): sc-47711 for FUS/TLS antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FUS/TLS Antibody (D-8) for WB and IHC(P) applications. These reagents are now offered in bundles with FUS/TLS Antibody (D-8) (see ordering information below).

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FUS/TLS Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects FUS/TLS in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). FUS/TLS, a nuclear RNA-binding protein, plays a crucial role in the regulation of gene expression and RNA processing, which is vital for maintaining cellular homeostasis and responding to stress signals. FUS/TLS antibody (D-8) recognizes a protein that interacts with nuclear steroid receptors, suggesting involvement in hormone-induced transcriptional regulation and various physiological processes. Additionally, FUS/TLS forms complexes with TFIID, indicating potential roles in transcriptional machinery and primary transcript processing. Chromosomal translocations causing aberrant fusion of FUS/TLS with other proteins can lead to oncogenic transformations, highlighting FUS/TLS′s significance in cancer research. Anti-FUS/TLS antibody (D-8) serves as a reliable tool for exploring functional dynamics in various biological contexts.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

FUS/TLS Antibody (D-8)

sc-373888
200 µg/ml
$316.00

FUS/TLS Antibody (D-8): m-IgG Fc BP-HRP Bundle

sc-537882
200 µg Ab; 10 µg BP
$354.00

FUS/TLS Antibody (D-8): m-IgGκ BP-HRP Bundle

sc-535330
200 µg Ab; 40 µg BP
$354.00

FUS/TLS Antibody (D-8): m-IgG1 BP-HRP Bundle

sc-545426
200 µg Ab; 20 µg BP
$354.00

Can FUS/TLS (D-8): sc-373888 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Dr Ninau Qelp
Thank you for your question. Yes, FUS/TLS (D-8): sc-373888 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_11, d_23, h_8CST
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Rated 5 out of 5 by from Good in WBUsed in transfected HeLa lysate and got a good signal.
Date published: 2017-10-19
Rated 5 out of 5 by from Beautiful immunofluorescence nuclear stainingBeautiful immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-02-09
Rated 5 out of 5 by from Strong band in western blot analysis of FUS/TLSStrong band in western blot analysis of FUS/TLS expression in THP-1 whole cell lysate. -SCBT QC
Date published: 2015-01-18
  • y_2025, m_11, d_23, h_8
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FUS/TLS Antibody (D-8) is rated 5.0 out of 5 by 3.
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