Fumonisin Antibody (2A2) is a mouse monoclonal IgG1 antibody that detects Fumonisin protein of non-species reactive by enzyme-linked immunosorbent assay (ELISA). Anti-Fumonisin antibody (2A2) is available as non-conjugated format, providing a reliable tool for researchers studying mycotoxins. Fumonisin, primarily produced by Fusarium species, is a significant mycotoxin that poses serious health risks, particularly in agricultural products like maize and wheat. Fumonisin disrupts sphingolipid metabolism, which is crucial for maintaining cellular integrity and function. Such disruption can lead to various health issues, including cardiovascular dysfunction and damage to vital organs such as liver and kidneys. Understanding Fumonisin toxicity mechanisms is essential for developing strategies to mitigate effects in food safety and public health. Anti-Fumonisin antibody (2A2) serves as an invaluable resource for detecting and quantifying this harmful mycotoxin in various samples, aiding in ongoing research and monitoring of food contaminants.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Fumonisin Antibody (2A2) References:
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- Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. | Marasas, WF., et al. 2004. J Nutr. 134: 711-6. PMID: 15051815
- Review: HPLC determination of fumonisin mycotoxins. | Arranz, I., et al. 2004. Crit Rev Food Sci Nutr. 44: 195-203. PMID: 15239373
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- Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. | Stockmann-Juvala, H., et al. 2004. Toxicology. 202: 173-83. PMID: 15337581
- Distribution of fumonisins and aflatoxins in corn fractions during industrial cornflake processing. | Castells, M., et al. 2008. Int J Food Microbiol. 123: 81-7. PMID: 18261815
- Fumonisin concentrations and in vivo toxicity of nixtamalized Fusarium verticillioides culture material: evidence for fumonisin-matrix interactions. | Burns, TD., et al. 2008. Food Chem Toxicol. 46: 2841-8. PMID: 18602734
- Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice. | Cuzzocrea, S., et al. 2009. Shock. 31: 170-7. PMID: 18650782
- Fumonisin mycotoxin contamination of corn-based foods consumed by potentially pregnant women in southern California. | Dvorak, NJ., et al. 2008. J Reprod Med. 53: 672-6. PMID: 18839819