FTCD Antibody (58K-9): sc-53128

FTCD Antibody (58K-9) is a mouse monoclonal IgG1 antibody that detects FTCD in mouse, rat, human, and canine samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). FTCD, or formiminotransferase-cyclodeaminase, is a bifunctional enzyme crucial for the metabolism of histidine, as FTCD facilitates the transfer of 1-carbon units from formiminoglutamate to the folate pool, thereby playing a significant role in one-carbon metabolism. This process is vital for DNA synthesis and repair, as well as for the production of neurotransmitters, which are essential for proper brain function. Deficiencies in FTCD can lead to glutamate formiminotransferase deficiency, an autosomal recessive disorder characterized by elevated levels of formiminoglutamate in urine, particularly after histidine administration, and can manifest in severe phenotypes such as megaloblastic anemia and cognitive impairments. Anti-FTCD antibody (58K-9) accurately identifies and quantifies FTCD, making this antibody an invaluable tool for researchers studying metabolic disorders and their implications on health.

The preferred FTCD antibody is FTCD Antibody (G-3): sc-271788.