FSHα Antibody (ME.111): sc-57149

FSHα Antibody (ME.111) is a mouse monoclonal IgG1 antibody that detects follicle-stimulating hormone (FSH) in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). FSH is a crucial glycoprotein hormone that plays a vital role in reproductive processes by regulating the development and function of ovarian follicles in females and spermatogenesis in males. FSH exists as a heterodimer, composed of a common alpha subunit and a unique beta subunit, which together facilitate binding to the follicle-stimulating hormone receptor (FSHR) on target cells. This interaction is essential for initiating signaling pathways that lead to the secretion of sex steroids and the maturation of gametes. FSH is primarily produced in the anterior pituitary gland and is localized to Sertoli cells in the testes, where FSH exerts effects on spermatogenesis. Precise regulation of FSH levels is critical for maintaining reproductive health, and dysregulation can lead to various fertility issues. Anti-FSHα antibody (ME.111) is an invaluable tool for researchers studying reproductive biology and related disorders, providing insights into the mechanisms of hormone action and potential therapeutic targets.