FOXN2 Antibody (D-4): sc-514664
- FOXN2 Antibody (D-4) is a mouse monoclonal IgM κ FOXN2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 62-85 within an internal region of FOXN2 of mouse origin
- recommended for detection of FOXN2 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-514664 X, 200 µg/0.1 ml)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FOXN2 Antibody (D-4). This work is in progress.
FOXN2 Antibody (D-4) is a mouse monoclonal IgM antibody that detects FOXN2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FOXN2 antibody (D-4) is available as the non-conjugated form. FOXN2, also known as Human T-cell leukemia virus enhancer factor, is a 341 amino acid protein encoded by the FOXN2 gene located on human chromosome 2p16-p22. FOXN2 plays a crucial role in gene expression regulation, particularly in the human T-cell leukemia virus long terminal repeat (HTLV-I LTR), binding to a purine-rich region essential for Ets family transcription factors activity. The forkhead domain-containing gene family, to which FOXN2 belongs, features a conserved 110 amino-acid motif forming a winged helix structure for specific DNA binding. This structural feature enables FOXN2 to act as a key regulator in various biological processes, including embryogenesis and cell lineage specification, as well as cancer progression. FOXN2′s interaction with other transcription factors highlights its importance in cellular signaling pathways and gene regulation, making anti-FOXN2 antibody (D-4) an invaluable research tool for studying these critical processes.
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FOXN2 Antibody (D-4) References:
- Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines. | Ariyama, Y., et al. 1999. J Hum Genet. 44: 357-63. PMID: 10570904
- Formation of regulator/target gene relationships during evolution. | Schlake, T., et al. 2000. Gene. 256: 29-34. PMID: 11054532
- Genetic dissection of thymus development in mouse and zebrafish. | Boehm, T., et al. 2003. Immunol Rev. 195: 15-27. PMID: 12969307
- Human FOX gene family (Review). | Katoh, M. and Katoh, M. 2004. Int J Oncol. 25: 1495-500. PMID: 15492844
- Characterization of human FOXN4 gene in silico. | Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 949-53. PMID: 15492871
- Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF. | Li, C., et al. 1992. Genomics. 13: 658-64. PMID: 1639393
- Temporal and spatial expression patterns of FoxN genes in Xenopus laevis embryos. | Schuff, M., et al. 2006. Int J Dev Biol. 50: 429-34. PMID: 16525939
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FOXN2 Antibody (D-4) | sc-514664 | 200 µg/ml | $322.00 | |||
FOXN2 (D-4) Neutralizing Peptide | sc-514664 P | 100 µg/0.5 ml | $69.00 | |||
FOXN2 Antibody (D-4) X | sc-514664 X | 200 µg/0.1 ml | $322.00 |