Flt-3/Flk-2 Antibody (8H5): sc-101343

Flt-3/Flk-2 Antibody (8H5) is a mouse monoclonal IgG1 antibody that detects Flt-3/Flk-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Flt-3/Flk-2, also known as stem cell tyrosine kinase (STK-1), plays a crucial role in hematopoiesis as a member of the type III receptor tyrosine kinase family, which includes other important receptors like Kit and PDGF. Flt-3/Flk-2 is primarily expressed in CD34+ hematopoietic stem and progenitor cells, where anti-Flt-3/Flk-2 antibody (8H5) can detect its function as a growth factor receptor influencing cell proliferation and differentiation. Flt-3/Flk-2′s location in these specific cell types highlights its involvement in regulating hematopoietic stem cell maintenance and blood cell lineage development. Flt-3/Flk-2 undergoes post-translational modifications, including phosphorylation, which are essential for activation and signaling capabilities. These modifications can impact receptor function and interactions with downstream signaling pathways, making Flt-3/Flk-2 monoclonal antibody (8H5) valuable for understanding hematological disorders and potential therapeutic interventions. Flt-3/Flk-2 (8H5) antibody provides reliable detection and characterization, supporting research in stem cell biology and related fields.

The preferred Flt-3/Flk-2 antibody is Flt-3/Flk-2 Antibody (SF1.340): sc-19635.