| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
VEGFR Tyrosine Kinase Inhibitor II | 269390-69-4 | sc-204378 | 5 mg | $212.00 | 1 | |
VEGFR Tyrosine Kinase Inhibitor II exhibits a selective interaction with the Flt receptor, characterized by its ability to disrupt ATP binding through competitive inhibition. This compound's unique structural features allow for specific electrostatic interactions with charged residues, modulating the receptor's kinase activity. Its conformational flexibility enables dynamic adjustments during binding, influencing the overall reaction kinetics and enhancing its inhibitory efficacy within cellular signaling networks. | ||||||
VEGFR Tyrosine Kinase Inhibitor V | 861874-34-2 anhydrous | sc-356190 | 5 mg | $240.00 | ||
VEGFR Tyrosine Kinase Inhibitor V demonstrates a remarkable affinity for the Flt receptor, engaging in allosteric modulation that alters the receptor's conformation. This compound's unique hydrophobic regions facilitate critical van der Waals interactions, enhancing binding stability. Its kinetic profile reveals a slow dissociation rate, allowing prolonged receptor occupancy. Additionally, the compound's solubility characteristics promote effective distribution within cellular environments, impacting downstream signaling pathways. | ||||||
AP 24534 HCl | 943319-70-8 free base | sc-396905 sc-396905A | 10 mg 50 mg | $112.00 $138.00 | ||
AP 24534 HCl exhibits a distinctive interaction with the Flt receptor through a dual binding mechanism that stabilizes its active conformation. The presence of polar functional groups enhances hydrogen bonding, contributing to its selectivity. Its reaction kinetics are characterized by a rapid association phase, followed by a gradual equilibrium, which allows for sustained receptor engagement. Furthermore, the compound's unique solvation dynamics facilitate efficient cellular uptake, influencing various signaling cascades. | ||||||