Filensin Antibody (R2D2): sc-69688

Filensin Antibody (R2D2) is a mouse monoclonal IgG1 antibody that detects Filensin in bovine samples through applications such as western blotting (WB) and immunofluorescence (IF). Filensin, also known as CP94, CP95, or CP97, is a vital cytoskeletal intermediate filament protein found in the eye lens fibers, where Filensin plays a crucial role in the assembly of beaded filaments and the maintenance of optical clarity. Filensin (R2D2) monoclonal antibody is essential for studying lens development, as Filensin regulates the shape conformation of lens fiber cells, thereby ensuring lens transparency. The unique structure of Filensin includes a C-terminal non-α-helical domain that is integral to functionality, while the head domain features a di-arginine/aromatic amino acid motif that harbors a potential phosphorylation site for protein kinase A, highlighting Filensin′s role in cellular signaling pathways. The interaction of Filensin with phakinin, another key protein, further emphasizes Filensin′s importance in forming the filamentous structures necessary for the lens′s structural integrity. Anti-Filensin antibody (R2D2) serves as an invaluable tool for researchers studying lens biology and related ocular conditions.

The preferred Filensin antibody is Filensin Antibody (IB38): sc-69689.