Fibrinogen γ Antibody (2.G2.H9): sc-81620

Fibrinogen γ Antibody (2.G2.H9) is a mouse monoclonal IgG1 antibody that detects Fibrinogen γ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunohistochemistry. Fibrinogen γ is one of the three subunits of the plasma glycoprotein Fibrinogen, which plays a crucial role in the coagulation cascade, particularly in the formation of Fibrin, the primary component of blood clots. Fibrinogen γ is synthesized in the liver and is essential for platelet aggregation, which is vital for hemostasis following tissue injury. Upon vascular damage, Fibrinogen is cleaved by Thrombin to generate Fibrin, and the resulting cleavage products not only facilitate cell adhesion and spreading but also exhibit vasoconstrictor and chemotactic properties, acting as mitogens for various cell types. The Fibrinogen γ subunit influences the structural integrity and functional properties of the Fibrin network, thereby impacting clot stability and wound healing processes. Anti-Fibrinogen γ antibody (2.G2.H9) is an invaluable tool for researchers studying coagulation disorders, cardiovascular diseases, and the inflammatory response, providing insights into the complex mechanisms of hemostasis and tissue repair.

The preferred Fibrinogen γ antibody is Fibrinogen γ Antibody (D-6): sc-133226.