Fibrinogen γ Antibody (D-6): sc-133226
- Fibrinogen γ Antibody (D-6) is a mouse monoclonal IgG1 κ Fibrinogen γ antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 27-220 mapping near the N-terminus of Fibrinogen γ of human origin
- Fibrinogen gamma Antibody (D-6) is recommended for detection of Fibrinogen γ-A and Fibrinogen γ-B of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Fibrinogen gamma Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Fibrinogen γ Antibody (D-6). This work is in progress.
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Fibrinogen γ Antibody (D-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Fibrinogen gamma protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Fibrinogen γ (D-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Fibrinogen gamma protein plays a crucial role in the coagulation process, as one of three subunits that make up plasma glycoprotein Fibrinogen, synthesized in the liver. Fibrinogen gamma protein is vital for platelet aggregation and Fibrin formation, the primary component of blood clots, essential for hemostasis following tissue injury. Fibrinogen gamma chain influences the structural integrity of Fibrin network, thereby affecting clot stability and wound healing. Additionally, Fibrinogen cleavage products, generated during coagulation cascade, have significant biological activities, including promoting cell adhesion and migration, which are critical for tissue repair and regeneration. Anti-Fibrinogen gamma antibody (D-6) serves as an invaluable tool for researchers studying coagulation, inflammation, and related pathologies, providing insights into hemostasis mechanisms and Fibrinogen′s role in various physiological and pathological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Fibrinogen γ Antibody (D-6) References:
- Blood rheology, cardiovascular risk factors, and cardiovascular disease: the West of Scotland Coronary Prevention Study. | Lowe, G., et al. 2000. Thromb Haemost. 84: 553-8. PMID: 11057849
- Fibrinogen--marker or mediator of vascular disease? | Reinhart, WH. 2003. Vasc Med. 8: 211-6. PMID: 14989564
- The coagulation cascade: initiation, maintenance, and regulation. | Davie, EW., et al. 1991. Biochemistry. 30: 10363-70. PMID: 1931959
- Basic mechanisms in blood coagulation. | Davie, EW. and Fujikawa, K. 1975. Annu Rev Biochem. 44: 799-829. PMID: 237463
- Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. | Danesh, J., et al. 1998. JAMA. 279: 1477-82. PMID: 9600484
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibrinogen γ Antibody (D-6) | sc-133226 | 200 µg/ml | $322.00 | |||
Fibrinogen γ Antibody (D-6) AC | sc-133226 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Fibrinogen γ Antibody (D-6) HRP | sc-133226 HRP | 200 µg/ml | $322.00 | |||
Fibrinogen γ Antibody (D-6) FITC | sc-133226 FITC | 200 µg/ml | $336.00 | |||
Fibrinogen γ Antibody (D-6) PE | sc-133226 PE | 200 µg/ml | $349.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 488 | sc-133226 AF488 | 200 µg/ml | $364.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 546 | sc-133226 AF546 | 200 µg/ml | $364.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 594 | sc-133226 AF594 | 200 µg/ml | $364.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 647 | sc-133226 AF647 | 200 µg/ml | $364.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 680 | sc-133226 AF680 | 200 µg/ml | $364.00 | |||
Fibrinogen γ Antibody (D-6) Alexa Fluor® 790 | sc-133226 AF790 | 200 µg/ml | $364.00 |